Epidemiological, clinical and evolutive profile of tuberculosis patients: Case of the region of Guelmim in Morocco

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Ahmed Oubaasri , Asmae Labyad , Fatima Zahra El mskini , Wafae Belokda , Aicha Madkour , Nouriya El Ghoulam , Daoud Daoudi , Aichetou Bouh , Slimane Mehdad , Souad Benaich
{"title":"Epidemiological, clinical and evolutive profile of tuberculosis patients: Case of the region of Guelmim in Morocco","authors":"Ahmed Oubaasri ,&nbsp;Asmae Labyad ,&nbsp;Fatima Zahra El mskini ,&nbsp;Wafae Belokda ,&nbsp;Aicha Madkour ,&nbsp;Nouriya El Ghoulam ,&nbsp;Daoud Daoudi ,&nbsp;Aichetou Bouh ,&nbsp;Slimane Mehdad ,&nbsp;Souad Benaich","doi":"10.1016/j.cegh.2024.101769","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and aim</h3><p>Tuberculosis is an infectious, contagious disease caused mainly by <em>Mycobacterium tuberculosis</em>. The objective of our study is to describe the epidemiological, clinical and evolutionary profiles of tuberculosis patients at the Diagnostic Center for Tuberculosis and Respiratory Diseases (DCTRD) in the Guelmim region, Morocco.</p></div><div><h3>Methods</h3><p>This is a retrospective study examining the medical records of tuberculosis patients at the Guelmim DCTRD from January 1, 2018, to April 28, 2022.</p></div><div><h3>Results</h3><p>A total of 825 cases were collected, comprising 488 cases of ETB and 337 cases of PTB. The median age of ETB patients was 31.5 [21–47] years, compared to 37 [26.5–52] years for PTB patients. ETB was more common than PTB in both age groups (&lt;10 and ≥ 10 years) (p &lt; 0.001). Females were more affected by ETB in 73 % of cases. Clinical signs were more prevalent in PTB than in ETB patients (p &lt; 0.001). Tobacco and alcohol consumption were higher in the PTB group than in the ETB group (p &lt; 0.001). Asthma and diabetes were more prevalent in the ETB group at 58 % and 51 %, respectively (p &lt; 0.001). HIV serology was largely negative in both groups, with a non-negligible proportion of unknown status (p &lt; 0.001). Therapeutic outcomes were favorable in 61 % of PTB patients versus 39 % of ETB patients (p &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>Our study highlighted the predominance of ETB. PTB patients had more clinical signs and tobacco/alcohol consumption. HIV serology was mostly negative, and therapeutic outcomes were favorable, suggesting a need for better management.</p></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213398424002665/pdfft?md5=379a0d8df141ca63a5372b973be5d815&pid=1-s2.0-S2213398424002665-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424002665","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0

Abstract

Background and aim

Tuberculosis is an infectious, contagious disease caused mainly by Mycobacterium tuberculosis. The objective of our study is to describe the epidemiological, clinical and evolutionary profiles of tuberculosis patients at the Diagnostic Center for Tuberculosis and Respiratory Diseases (DCTRD) in the Guelmim region, Morocco.

Methods

This is a retrospective study examining the medical records of tuberculosis patients at the Guelmim DCTRD from January 1, 2018, to April 28, 2022.

Results

A total of 825 cases were collected, comprising 488 cases of ETB and 337 cases of PTB. The median age of ETB patients was 31.5 [21–47] years, compared to 37 [26.5–52] years for PTB patients. ETB was more common than PTB in both age groups (<10 and ≥ 10 years) (p < 0.001). Females were more affected by ETB in 73 % of cases. Clinical signs were more prevalent in PTB than in ETB patients (p < 0.001). Tobacco and alcohol consumption were higher in the PTB group than in the ETB group (p < 0.001). Asthma and diabetes were more prevalent in the ETB group at 58 % and 51 %, respectively (p < 0.001). HIV serology was largely negative in both groups, with a non-negligible proportion of unknown status (p < 0.001). Therapeutic outcomes were favorable in 61 % of PTB patients versus 39 % of ETB patients (p < 0.001).

Conclusion

Our study highlighted the predominance of ETB. PTB patients had more clinical signs and tobacco/alcohol consumption. HIV serology was mostly negative, and therapeutic outcomes were favorable, suggesting a need for better management.

结核病患者的流行病学、临床和演变概况:摩洛哥盖尔米姆地区的案例
背景和目的结核病是一种主要由结核分枝杆菌引起的传染性疾病。我们的研究旨在描述摩洛哥盖尔米姆地区结核病和呼吸道疾病诊断中心(DCTRD)结核病患者的流行病学、临床和演变概况。方法这是一项回顾性研究,检查了2018年1月1日至2022年4月28日期间盖尔米姆地区结核病和呼吸道疾病诊断中心结核病患者的病历。ETB患者的中位年龄为31.5 [21-47]岁,而PTB患者的中位年龄为37 [26.5-52]岁。在两个年龄组(<10 岁和≥10 岁)中,ETB 都比 PTB 更常见(p <0.001)。73%的 ETB 患者为女性。临床症状在 PTB 患者中比在 ETB 患者中更为普遍(p < 0.001)。PTB 组的烟草和酒精消耗量高于 ETB 组(p < 0.001)。哮喘和糖尿病在 ETB 组的发病率更高,分别为 58% 和 51%(p <0.001)。两组患者的艾滋病毒血清学检测结果均为阴性,但也有一定比例的患者血清学检测结果未知(p < 0.001)。61%的 PTB 患者治疗效果良好,而 39% 的 ETB 患者治疗效果不佳(p < 0.001)。PTB 患者有更多的临床症状和吸烟/饮酒。艾滋病病毒血清学检查大多为阴性,治疗效果良好,这表明需要更好的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.60
自引率
7.70%
发文量
218
审稿时长
66 days
期刊介绍: Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信