Accelerating Progress to Reduce the Cancer Burden through Prevention and Control in the US.

IF 9.9 1区医学 Q1 ONCOLOGY

JNCI Journal of the National Cancer Institute Pub Date : 2024-09-03 DOI:10.1093/jnci/djae204

Katrina A B Goddard, Eric J Feuer, Asad Umar, Philip E Castle

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引用次数: 0

Abstract

Improvements in cancer prevention and control are poised to be main contributors in reducing the burden of cancer in the US. We quantify top opportunities to accelerate progress using projected life years gained (LYG) and deaths averted as measures. We project that over the next 25 years, realistic gains from tobacco control can contribute 0.4 to 17 million additional LYG per intervention and 8.4 million additional LYG from improving uptake of screening programs over the lifetime of 25 annual cohorts. Additional opportunities include addressing modifiable risk factors (excess weight, alcohol consumption), improving methods to prevent or treat oncogenic infections, and reducing cancer health disparities. Investment is needed in the pipeline of new preventive agents and technologies for early detection to continue progress. There is also a need for additional research to improve the access to and uptake of existing and emerging interventions for cancer prevention and control and to address health disparities. These gains are undeniably within our power to realize for the US population.

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美国通过预防和控制加快减轻癌症负担的进度。

癌症预防和控制方面的改进有望成为减轻美国癌症负担的主要因素。我们用预计获得的生命年数（LYG）和避免的死亡人数作为衡量标准，量化了加快进展的最佳机会。我们预测，在未来 25 年内，烟草控制的实际收益可使每次干预增加 40 万到 1700 万年的寿命，而在 25 个年度队列的生命周期内，提高筛查项目的接受率可使寿命增加 840 万年。其他机会还包括应对可改变的风险因素（超重、饮酒）、改进预防或治疗致癌感染的方法以及减少癌症的健康差异。需要对新的预防药物和早期检测技术进行投资，以继续取得进展。此外，还需要开展更多的研究，以改善现有和新出现的癌症预防和控制干预措施的获取和吸收，并解决健康差异问题。不可否认，我们有能力为美国人民实现这些成果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JNCI Journal of the National Cancer Institute 医学-肿瘤学

CiteScore

17.00

自引率

2.90%

发文量

203

审稿时长

4-8 weeks

期刊介绍： The Journal of the National Cancer Institute is a reputable publication that undergoes a peer-review process. It is available in both print (ISSN: 0027-8874) and online (ISSN: 1460-2105) formats, with 12 issues released annually. The journal's primary aim is to disseminate innovative and important discoveries in the field of cancer research, with specific emphasis on clinical, epidemiologic, behavioral, and health outcomes studies. Authors are encouraged to submit reviews, minireviews, and commentaries. The journal ensures that submitted manuscripts undergo a rigorous and expedited review to publish scientifically and medically significant findings in a timely manner.