Post-Transplant Lymphoproliferative Disorder Presenting as a Gastrointestinal Fistulous Tract in a Heart Transplant Recipient: Case Report and Literature Review.

Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-08-30 DOI:10.1016/j.transproceed.2024.07.008
Nour Hasan, Ramia Zakhour, Luz Helena Gutierrez Sanchez, Audrey R Lloyd, Geling Li, Clara L Ortiz, Cecelia Hutto
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引用次数: 0

Abstract

We present a challenging case of Epstein-Barr virus-related isolated small bowel post-transplant lymphoproliferative disorder (PTLD) in a pediatric heart transplant recipient presenting as recurrent gastrointestinal (GI) bleeding and subsequently a GI fistulous tract with associated intra-abdominal abscess. Diagnosis was not confirmed until exploratory laparoscopy was performed, with excision of the fistulous tract revealing evidence of PTLD on pathology. Early diagnosis of GI-PTLD remains a challenge, especially if isolated in the small intestine. Diagnosis may rely on positron emission tomography/ computed tomography scan (PET/CT) or invasive intervention to obtain appropriate tissue samples for pathology diagnosis.

一名心脏移植受者移植后出现胃肠道瘘管的淋巴组织增生性疾病:病例报告和文献综述。
我们介绍了一例与爱泼斯坦-巴氏病毒(Epstein-Barr virus)相关的小肠移植后淋巴组织增生性疾病(PTLD)病例,该病例为小儿心脏移植受者,表现为反复消化道出血,随后出现消化道瘘道并伴有腹腔内脓肿。直到进行了探查性腹腔镜检查后才确诊,病理检查发现瘘管有PTLD的证据。消化道PTLD的早期诊断仍是一项挑战,尤其是在小肠中分离出PTLD时。诊断可能有赖于正电子发射断层扫描/计算机断层扫描(PET/CT)或侵入性干预,以获取适当的组织样本进行病理诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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