Post-extraction bleeding in patients on direct oral anticoagulants.

IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of the Korean Association of Oral and Maxillofacial Surgeons Pub Date : 2024-08-31 DOI:10.5125/jkaoms.2024.50.4.189

Min-Ji Kim, Moon-Key Kim, Sang-Hoon Kang

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引用次数: 0

Abstract

Objectives: This study aimed to evaluate the association between use of direct oral anticoagulants (DOACs) and post-extraction bleeding and to quantify bleeding risk in patients receiving DOACs.

Materials and methods: The study included 293 patients who were taking DOACs and underwent tooth extraction (414 teeth). The patients were divided into those who had the extraction while taking DOACs and those who discontinued DOACs before the extraction. Bleeding complications were recorded and compared between the patient groups and types of DOACs.

Results: Of the 293 patients, 12 patients (6.9%) had post-extraction bleeding. Post-extraction bleeding occurred in 12 of the 414 tooth extraction sites. Among the 246 patients who underwent dental extraction while continuing DOAC therapy, 12 patients (8.5%) had post-extraction bleeding. Among the 47 patients who underwent dental extraction after discontinuing the administration of DOACs, none reported post-extraction bleeding. There was no significant difference in the number of patients with post-extraction bleeding between the two groups (P=0.122).

Conclusion: Continuing DOAC therapy during dental extraction does not increase post-extraction bleeding tendency. These results are consistent with those of previous studies.

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服用直接口服抗凝剂的患者拔牙后出血。

研究目的本研究旨在评估使用直接口服抗凝剂（DOACs）与拔牙后出血之间的关联，并量化接受 DOACs 患者的出血风险：研究包括 293 名服用 DOACs 并接受拔牙（414 颗牙齿）的患者。患者分为在服用 DOACs 期间拔牙的患者和在拔牙前停用 DOACs 的患者。对出血并发症进行了记录，并对患者组别和 DOACs 类型进行了比较：在293名患者中，有12名患者（6.9%）发生了拔牙后出血。拔牙后出血发生在 414 个拔牙部位中的 12 个。在继续接受 DOAC 治疗的 246 名拔牙患者中，有 12 名患者（8.5%）出现拔牙后出血。在停用 DOAC 后进行拔牙的 47 名患者中，没有人报告拔牙后出血。两组患者拔牙后出血的人数无明显差异（P=0.122）：结论：拔牙期间继续使用 DOAC 不会增加拔牙后出血倾向。这些结果与之前的研究结果一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Korean Association of Oral and Maxillofacial Surgeons DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

2.00

自引率

10.00%

发文量

期刊介绍： Journal of the Korean Association of Oral and Maxillofacial Surgeons (J Korean Assoc Oral Maxillofac Surg) is the official journal of the Korean Association of Oral and Maxillofacial Surgeons. This bimonthly journal offers high-quality original articles, case series study, case reports, collective or current reviews, technical notes, brief communications or correspondences, and others related to regenerative medicine, dentoalveolar surgery, dental implant surgery, head and neck cancer, aesthetic facial surgery/orthognathic surgery, facial injuries, temporomandibular joint disorders, orofacial disease, and oral pathology. J Korean Assoc Oral Maxillofac Surg is of interest to oral and maxillofacial surgeons and dental practitioners as well as others who are interested in these fields.