Exploring the importance of family socio-economic position on the association between parental BMI and offspring BMI trajectories

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Jie Zhang PhD , Gemma L. Clayton PhD , Kim Overvad PhD , Anja Olsen PhD , Deborah A. Lawlor PhD , Christina C. Dahm PhD
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Abstract

Purpose

We aimed to investigate the associations between parental BMI and offspring BMI trajectories and to explore whether the parent-offspring BMI growth trajectory association differed according to family SEP or social mobility.

Methods

We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Children’s weight and height were collected from 1 to 18 years. Parents’ height and weight were reported pre-pregnancy. We assessed family SEP by measuring parents’ and grandparents’ educational attainment, social class, and social mobility by changes in education attainment across generations. Multilevel models were used to develop trajectories and assess patterns of change in offspring BMI, to associate parental BMI with these trajectories, and explore whether these associations differed by family SEP and social mobility.

Results

13,612 children were included in the analyses. The average BMI of offspring whose parents were overweight or obese was higher throughout childhood and adolescence, compared to those with parents of normal BMI. Parental and grandparental low SEP were associated with higher child BMI, but there was little evidence of modification of parent-offspring associations. For example, at age 15 years the predicted mean BMI difference between children of overweight or obese mothers versus normal-weight mothers was 12.5 % (95 %CI: 10.1 % to 14.7 %) and 12.2 % (95 %CI: 10.3 % to 13.7 %) for high and low grandparental SEP, respectively.

Discussion

These findings strengthen the evidence that higher parental BMI and lower family SEP were associated with higher offspring BMI, but we did not observe strong evidence that family SEP modifies the parental-offspring BMI association.

探索家庭社会经济地位对父母体重指数与后代体重指数轨迹之间关联的重要性。
目的:我们旨在研究父母体重指数(BMI)与后代体重指数(BMI)增长轨迹之间的关联,并探讨父母与后代体重指数(BMI)增长轨迹的关联是否因家庭SEP或社会流动性而有所不同:我们使用了雅芳父母与子女纵向研究(ALSPAC)的数据。我们收集了 1 至 18 岁儿童的体重和身高数据。父母的身高和体重是在怀孕前报告的。我们通过测量父母和祖父母的教育程度、社会阶层和社会流动性来评估家庭SEP。我们使用多层次模型来建立后代体重指数的变化轨迹并评估其变化模式,将父母的体重指数与这些轨迹联系起来,并探讨这些联系是否因家庭SEP和社会流动性而有所不同:13,612 名儿童被纳入分析。与父母体重指数正常的儿童相比,父母超重或肥胖的儿童在整个童年和青少年时期的平均体重指数较高。父母和祖父母的低 SEP 与儿童较高的体重指数有关,但几乎没有证据表明父母与后代之间的关联会发生改变。例如,在 15 岁时,超重或肥胖母亲的子女与体重正常母亲的子女之间的预测平均体重指数差异分别为 12.5%(95%CI:10.1% 至 14.7%)和 12.2%(95%CI:10.3% 至 13.7%),而祖父母 SEP 高和祖父母 SEP 低的子女的预测平均体重指数差异分别为 12.5%(95%CI:10.1% 至 14.7%)和 12.2%(95%CI:10.3% 至 13.7%):这些发现加强了父母较高的体重指数和较低的家庭 SEP 与后代较高的体重指数相关的证据,但我们没有观察到家庭 SEP 改变父母-后代体重指数相关性的有力证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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