Ruijia Chen, DeAnnah R Byrd, Keith E Whitfield, David R Williams
{"title":"Associations of Major Lifetime and Everyday Discrimination with Cognitive Function among Middle-Aged and Older Adults.","authors":"Ruijia Chen, DeAnnah R Byrd, Keith E Whitfield, David R Williams","doi":"10.18865/EthnDis-2023-42","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>We investigated the associations of lifetime and everyday discrimination with cognitive function.</p><p><strong>Methods: </strong>Data were from the Chicago Community Adult Health Study (n=2952, mean age=43 years [SD=17]). We fitted multivariable linear regression models to quantify the discrimination-cognition associations.</p><p><strong>Results: </strong>Major lifetime (<i>β<sub>1 vs 0 episodes of discrimination</sub></i> = 0.56; 95% CI, 0.15-0.96; <i>β<sub>2+ vs 0 episodes of discrimination</sub></i> = 0.64, 95% CI, 0.31-0.97) and everyday (<i>β</i>=0.10, 95% CI, 0.06-0.14) discrimination were positively associated with cognition, and these associations did not differ by race/ethnicity. Among older adults, major lifetime discrimination, but not everyday discrimination, was positively associated with cognition (<i>β<sub>2+ vs 0 episodes of discrimination</sub></i> =1.79; 95% CI, 0.79-2.79).</p><p><strong>Discussion: </strong>Measurement and selection bias may partially explain the counterintuitive study findings. We call for longitudinal research to further investigate the discrimination-cognition relationship.</p>","PeriodicalId":50495,"journal":{"name":"Ethnicity & Disease","volume":null,"pages":null},"PeriodicalIF":3.4000,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11354826/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ethnicity & Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18865/EthnDis-2023-42","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: We investigated the associations of lifetime and everyday discrimination with cognitive function.
Methods: Data were from the Chicago Community Adult Health Study (n=2952, mean age=43 years [SD=17]). We fitted multivariable linear regression models to quantify the discrimination-cognition associations.
Results: Major lifetime (β1 vs 0 episodes of discrimination = 0.56; 95% CI, 0.15-0.96; β2+ vs 0 episodes of discrimination = 0.64, 95% CI, 0.31-0.97) and everyday (β=0.10, 95% CI, 0.06-0.14) discrimination were positively associated with cognition, and these associations did not differ by race/ethnicity. Among older adults, major lifetime discrimination, but not everyday discrimination, was positively associated with cognition (β2+ vs 0 episodes of discrimination =1.79; 95% CI, 0.79-2.79).
Discussion: Measurement and selection bias may partially explain the counterintuitive study findings. We call for longitudinal research to further investigate the discrimination-cognition relationship.
期刊介绍:
Ethnicity & Disease is an international journal that exclusively publishes information on the causal and associative relationships in the etiology of common illnesses through the study of ethnic patterns of disease. Topics focus on: ethnic differentials in disease rates;impact of migration on health status; social and ethnic factors related to health care access and health; and metabolic epidemiology. A major priority of the journal is to provide a forum for exchange between the United States and the developing countries of Europe, Africa, Asia, and Latin America.