Recent progress in one-pot enzymatic synthesis and regeneration of high-value cofactors.

IF 14.3 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2024-08-29 DOI:10.1016/j.tibtech.2024.08.006

I-Son Ng, Po-Hsiang Wang, Wan-Wen Ting, Jiun-Jang Juo

引用次数: 0

Abstract

One-pot enzymatic synthesis is flourishing in synthetic chemistry, heralding a sustainable and green era. Recent advancements enable the creation of complex enzymatic prosthetic groups and regeneration of enzymatic cofactors such as S-adenosylmethionine. The next frontier is to develop the effective and innovative cofactors for essential micronutrients, metabolic modulators, and biomedicines.

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一步酶法合成和再生高价值辅助因子的最新进展。

单锅酶法合成在合成化学领域蓬勃发展，预示着一个可持续发展的绿色时代的到来。最近的进展使得复杂的酶修复基团和酶辅助因子（如 S-腺苷蛋氨酸）的再生成为可能。下一个前沿领域是为必需微量元素、代谢调节剂和生物药物开发有效的创新辅助因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).