Visible Light-Mediated Carbamoylation of para-Quinone Methides

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2023-02-15 DOI:10.1021/acs.joc.2c02394

Tavinder Singh, Ganesh Chandra Upreti, Shivani Arora, Himanshu Chauhan and Anand Singh*,

引用次数: 1

Abstract

We report a photocatalytic approach for the installation of the amide moiety onto para-quinone methides. This transformation features a net reductive approach for the generation of carbamoyl radicals from amide-substituted Hantzsch ester derivatives under transition metal-free conditions. This protocol exhibits wide scope and allows access to diarylacetamides employing a C–C bond formation approach.

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可见光介导的对醌甲氨甲酰化

我们报道了一种光催化方法将酰胺部分安装到对醌类化合物上。这种转变的特点是在无过渡金属的条件下，从酰胺取代的汉奇酯衍生物生成氨基甲酰自由基的净还原方法。该协议具有广泛的适用范围，并允许使用C-C键形成方法获得二芳基乙酰胺。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.