Long-Term Outcomes of Modified Endoscopic Transcanal Approach to Small Acoustic Tumors.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-08-29 DOI:10.1097/MAO.0000000000004302
Riana Kipiani Abdul Halim, Gerard Lapina, Seung Ho Shin, Youngrak Jung, Jeong Gum Lee, In Seok Moon
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引用次数: 0

Abstract

Objective: The management options for small acoustic tumors are still controversial, and surgery is indicated in a select number of patients only. This is to avoid unnecessary extensive operations and risk of complications. Endoscopic transcanal approach, which was recently introduced, can be an alternative option to overcome these challenges. We have developed a modified technique for endoscopic transcanal removal of small acoustic tumors with tympanoplasty using tragal cartilage and without the need to harvest abdominal fat for obliteration. There was also no need to do an ear cul-de-sac procedure compared with the previous method. We report the long-term outcomes of this approach.

Study design: Retrospective review.

Setting: Tertiary hospital.

Patients: Those who were diagnosed with small acoustic tumors between June 2016 and June 2022 were enrolled.

Interventions: Tumor removal via a Modified Endoscopic Transcanal Transpromontorial Approach (mETTA).

Main outcome measure: Tumor control rate, closure rate of tympanic membrane, and complications such as cerebrospinal fluid (CSF) leakage and facial palsy were analyzed. Operation time and hospital stay were also analyzed.

Results: Twenty-two patients with a mean age of 55.5 ± 9.4 years were enrolled. Eighteen were vestibular schwannomas (VS), two were intracochlear schwannomas (ICS), and two were with intravestibulocochlear schwannomas (IVCS). Gross total removal was achieved in 21 cases. One had developed significant CSF leakage, and the other patient complicated with permanent facial palsy. The tympanic membrane healed well in all patients, but three patients showed delayed healing until several months and treated conservatively. Mean operation time was 149.6 ± 48.4 minutes, mean hospital stay was 8.9 ± 4.5 days, and mean postoperative follow-up period was 42.0 ± 15.7 months.

Conclusion: Long-term results of modified endoscopic transcanal approach to small acoustic tumors are acceptable and comparable to classical treatments such as translabyrinthine approach or gamma knife radiation. This is an alternative option for smaller tumors warranting surgical removal and maintained cosmetic advantages.

改良内镜经鼻小肿瘤手术的长期疗效
目的:小型听觉肿瘤的治疗方案仍存在争议,只有少数患者适合手术治疗。这是为了避免不必要的大范围手术和并发症风险。最近推出的内窥镜经腔方法可以作为克服这些挑战的另一种选择。我们开发了一种改良技术,利用耳廓软骨进行鼓室成形术,在内窥镜下经耳道切除小的听神经瘤,且无需采集腹部脂肪进行阻塞。与之前的方法相比,这种方法也无需进行耳内手术。我们报告了这种方法的长期疗效:背景:三级医院患者患者:2016年6月至2022年6月期间确诊为小型听觉肿瘤的患者:主要结果指标:分析肿瘤控制率、鼓膜闭合率以及脑脊液(CSF)漏和面瘫等并发症。此外,还分析了手术时间和住院时间:22例患者的平均年龄为(55.5±9.4)岁。18例为前庭裂神经瘤(VS),2例为耳蜗内裂神经瘤(ICS),2例为耳蜗内裂神经瘤(IVCS)。21 个病例实现了彻底切除。其中一名患者出现了严重的脑脊液渗漏,另一名患者则并发了永久性面瘫。所有患者的鼓膜愈合良好,但有三名患者的鼓膜愈合延迟至数月后才愈合,并接受了保守治疗。平均手术时间为(149.6 ± 48.4)分钟,平均住院时间为(8.9 ± 4.5)天,平均术后随访时间为(42.0 ± 15.7)个月:结论:改良内镜下经颅入路治疗小型听神经肿瘤的长期效果是可以接受的,与传统治疗方法(如迷宫入路或伽玛刀放射治疗)不相上下。对于需要手术切除的较小肿瘤来说,这是一种可供选择的方法,而且还能保持外观上的优势。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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