Multiple ASM Administration via Percutaneous Feeding Tube as a Cause of Pseudo-Refractoriness Leading to Recurrent Seizure Clusters.

IF 0.9 3区医学 Q4 NEUROSCIENCES

Neurology India Pub Date : 2024-07-01 Epub Date: 2024-08-31 DOI:10.4103/neurol-india.ni_1146_22

Swetha Ambarapu, Rima Chaudhari

引用次数: 0

Abstract

It is important to identify true refractoriness of seizures, before escalation of anti-seizure medications, to avoid side effects of medications. Bioavailability of medications changes with the formulations used and changes significantly with the route of administration. Both of these were significantly impacted in a lady who was being fed via percutaneous endoscopic gastrostomy (PEG) feeds and deemed refractory to medications. After altering the formulations and the method, she became seizure-free.

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经皮喂食管多次给药 ASM 是导致癫痫复发的假性难治性的原因之一。

在升级抗癫痫药物之前，必须确定癫痫发作的真正折射性，以避免药物的副作用。药物的生物利用度会随着所使用的配方而改变，并随着给药途径的不同而发生显著变化。一位通过经皮内镜胃造瘘术（PEG）喂养并被认为对药物难治的女士在这两方面都受到了很大影响。在改变配方和方法后，她的癫痫不再发作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurology India 医学-神经科学

CiteScore

1.60

自引率

70.40%

发文量

434

审稿时长

2 months

期刊介绍： Neurology India (ISSN 0028-3886) is Bi-monthly publication of Neurological Society of India. Neurology India, the show window of the progress of Neurological Sciences in India, has successfully completed 50 years of publication in the year 2002. ‘Neurology India’, along with the Neurological Society of India, has grown stronger with the passing of every year. The full articles of the journal are now available on internet with more than 20000 visitors in a month and the journal is indexed in MEDLINE and Index Medicus, Current Contents, Neuroscience Citation Index and EMBASE in addition to 10 other indexing avenues. This specialty journal reaches to about 2000 neurologists, neurosurgeons, neuro-psychiatrists, and others working in the fields of neurology.