Neuropathic Pain Component in Patients with Ankylosing Spondylitis and the Relationship of Neuropathic Pain and Disease Activity Parameters: A Cross-Sectional Study.

IF 1.7 4区医学 Q4 NEUROSCIENCES

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-09-01

Seda Atik, Ozlem Sahin, Irfan Atik, Musa Polat

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引用次数: 0

Abstract

Objective: It is known that neuropathic pain frequently accompanies rheumatological diseases. In this study, neuropathic pain in Ankylosing Spondylitis(AS) and its relationship with disease activity were investigated.

Methods: Forty patients with AS were included. Laboratory data and disease status parameters were recorded. Neuropathic pain questionnaires were administered. Electrophysiological examination was performed on all patients. The relationship between neuropathic pain and disease activity parameters was investigated.

Results: According to the Pain Detect and LANSS questionnaire results, the rate of neuropathic pain was 57.5% and 42.5%. ASQoL, BASDAI, and ASDAS-ESH parameters are statistically significantly higher in the group with neuropathic pain according to the PainDetect (p:0.018, p:0.04, p:0.028). MASES, ASQoL, BASDAI, BASFI, and ASDAS-ESH parameters are statistically significantly higher in the group with neuropathic pain according to the LANSS (p:0.004, p:0.005, p: 0.001, p:0.005, p:0.02). Disease activity is higher in patients with neuropathic pain for both scales. Peripheral neuropathy is detected in nine patients. There is a positive correlation between disease activity parameters and neuropathic pain scales. A strong positive correlation was detected between ASQoL and BASDAI parameters and the Pain Detect questionnaire (r:0.533, r:0.606).

Conclusions: The majority of patients with AS have a neuropathic pain. This condition is associated with high disease activity and adversely affects the patient's quality of life.

本刊更多论文

强直性脊柱炎患者的神经病理性疼痛成分以及神经病理性疼痛与疾病活动参数的关系：一项横断面研究

目的：众所周知，神经性疼痛经常伴随风湿病。本研究调查了强直性脊柱炎（AS）患者的神经病理性疼痛及其与疾病活动的关系：方法：纳入 40 名强直性脊柱炎患者。方法：纳入 40 名强直性脊柱炎患者，记录实验室数据和疾病状态参数。进行神经病理性疼痛问卷调查。对所有患者进行电生理检查。研究了神经性疼痛与疾病活动参数之间的关系：结果：根据疼痛检测和 LANSS 问卷调查结果，神经病理性疼痛发生率分别为 57.5%和 42.5%。根据疼痛检测结果，神经病理性疼痛组的 ASQoL、BASDAI 和 ASDAS-ESH 参数在统计学上明显更高（P:0.018、P:0.04、P:0.028）。根据 LANSS，神经病理性疼痛组的 MASES、ASQoL、BASDAI、BASFI 和 ASDAS-ESH 参数在统计学上明显更高（p:0.004、p:0.005、p: 0.001、p:0.005、p:0.02）。在两种量表中，神经病理性疼痛患者的疾病活动度都较高。九名患者发现了周围神经病变。疾病活动性参数与神经病理性疼痛量表呈正相关。ASQoL 和 BASDAI 参数与疼痛检测问卷（r:0.533, r:0.606）之间存在很强的正相关性：结论：大多数强直性脊柱炎患者有神经性疼痛。结论：大多数强直性脊柱炎患者都有神经病理性疼痛，这种情况与疾病的高度活动性有关，并对患者的生活质量产生不利影响。

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来源期刊

Journal of musculoskeletal & neuronal interactions NEUROSCIENCES-PHYSIOLOGY

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.