The effect of open-label placebo on allergic rhinitis symptoms: A systematic review and meta-analysis of randomized controlled trials.

IF 7.2 2区医学 Q1 OTORHINOLARYNGOLOGY

International Forum of Allergy & Rhinology Pub Date : 2025-01-01 Epub Date: 2024-08-30 DOI:10.1002/alr.23444

Ebraheem Albazee, Abdullah M Alharran, Mooza M Alzayed

引用次数: 0

Abstract

Key points: The evidence regarding the open-label placebo effect on allergic rhinitis symptoms remains uncertain. Open-label placebo significantly reduced the frequency of symptoms in allergic rhinitis patients with similar safety profiles; however, there was no effect on the severity of symptoms and impairment due to symptoms. The statistically significant impact on symptom frequency can be considered not clinically significant.

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开放标签安慰剂对过敏性鼻炎症状的影响：随机对照试验的系统回顾和荟萃分析。

要点：有关开放标签安慰剂对过敏性鼻炎症状影响的证据仍不确定。在安全性相似的情况下，开放标签安慰剂能明显降低过敏性鼻炎患者的症状频率；但对症状的严重程度和症状造成的损害没有影响。从统计学角度看，对症状频率的影响并无临床意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Forum of Allergy & Rhinology OTORHINOLARYNGOLOGY-

CiteScore

11.70

自引率

10.90%

发文量

185

审稿时长

6-12 weeks

期刊介绍： International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy. International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.