SCINet: A Segmentation and Classification Interaction CNN Method for Arteriosclerotic Retinopathy Grading.

IF 3.9 2区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Xiongwen Quan, Xingyuan Ou, Li Gao, Wenya Yin, Guangyao Hou, Han Zhang
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引用次数: 0

Abstract

As a common disease, cardiovascular and cerebrovascular diseases pose a great harm threat to human wellness. Even using advanced and comprehensive treatment methods, there is still a high mortality rate. Arteriosclerosis, as an important factor reflecting the severity of cardiovascular and cerebrovascular diseases, is imperative to detect the arteriosclerotic retinopathy. However, the detection of arteriosclerosis retinopathy requires expensive and time-consuming manual evaluation, while end-to-end deep learning detection methods also need interpretable design to high light task-related features. Considering the importance of automatic arteriosclerotic retinopathy grading, we propose a segmentation and classification interaction network (SCINet). We propose a segmentation and classification interaction architecture for grading arteriosclerotic retinopathy. After IterNet is used to segment retinal vessel from original fundus images, the backbone feature extractor roughly extracts features from the segmented and original fundus arteriosclerosis images and further enhances them through the vessel aware module. The last classifier module generates fundus arteriosclerosis grading results. Specifically, the vessel aware module is designed to highlight the important areal vessel features segmented from original images by attention mechanism, thereby achieving information interaction. The attention mechanism selectively learns the vessel features of segmentation region information under the proposed interactive architecture, which leads to reweighting the extracted features and enhances significant feature information. Extensive experiments have confirmed the effect of our model. SCINet has the best performance on the task of arteriosclerotic retinopathy grading. Additionally, the CNN method is scalable to similar tasks by incorporating segmented images as auxiliary information.

Abstract Image

SCINet:用于动脉硬化性视网膜病变分级的分割与分类交互 CNN 方法。
心脑血管疾病作为一种常见病,对人类健康造成了极大的危害。即使采用先进的综合治疗方法,死亡率仍然很高。动脉硬化作为反映心脑血管疾病严重程度的重要因素,对动脉硬化性视网膜病变的检测势在必行。然而,动脉硬化性视网膜病变的检测需要昂贵而耗时的人工评估,而端到端的深度学习检测方法也需要对高亮任务相关特征进行可解释性设计。考虑到动脉硬化性视网膜病变自动分级的重要性,我们提出了一种分割与分类交互网络(SCINet)。我们提出了一种用于动脉硬化性视网膜病变分级的分割与分类交互架构。在使用 IterNet 从原始眼底图像中分割出视网膜血管后,主干特征提取器从分割后的原始眼底动脉硬化图像中粗略提取特征,并通过血管感知模块进一步增强这些特征。最后一个分类器模块生成眼底动脉硬化分级结果。具体来说,血管感知模块旨在通过注意力机制,突出从原始图像中分割出的重要区域血管特征,从而实现信息交互。在所提出的交互式架构下,注意力机制会选择性地学习分割区域信息中的血管特征,从而对提取的特征进行重新加权,增强重要的特征信息。大量实验证实了我们模型的效果。SCINet 在动脉硬化性视网膜病变分级任务中表现最佳。此外,通过将分割图像作为辅助信息,CNN 方法还可扩展到类似任务。
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来源期刊
Interdisciplinary Sciences: Computational Life Sciences
Interdisciplinary Sciences: Computational Life Sciences MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
8.60
自引率
4.20%
发文量
55
期刊介绍: Interdisciplinary Sciences--Computational Life Sciences aims to cover the most recent and outstanding developments in interdisciplinary areas of sciences, especially focusing on computational life sciences, an area that is enjoying rapid development at the forefront of scientific research and technology. The journal publishes original papers of significant general interest covering recent research and developments. Articles will be published rapidly by taking full advantage of internet technology for online submission and peer-reviewing of manuscripts, and then by publishing OnlineFirstTM through SpringerLink even before the issue is built or sent to the printer. The editorial board consists of many leading scientists with international reputation, among others, Luc Montagnier (UNESCO, France), Dennis Salahub (University of Calgary, Canada), Weitao Yang (Duke University, USA). Prof. Dongqing Wei at the Shanghai Jiatong University is appointed as the editor-in-chief; he made important contributions in bioinformatics and computational physics and is best known for his ground-breaking works on the theory of ferroelectric liquids. With the help from a team of associate editors and the editorial board, an international journal with sound reputation shall be created.
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