Behavioral economic analysis of the comorbidity of alcohol problems and posttraumatic stress: Findings from high-risk young adults and general community adults.

IF 2.4 3区 医学 Q3 PHARMACOLOGY & PHARMACY
Brian M Bird, Kyla Belisario, James G Murphy, Sherry H Stewart, James MacKillop
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引用次数: 0

Abstract

A behavioral economic reinforcer pathology model theorizes that alcohol problems are influenced by steep delay discounting, overvaluation of alcohol reinforcement, and low reinforcement from alcohol-free activities. Extending this account to the comorbidity of alcohol problems and posttraumatic stress disorder (PTSD), the present study tested the hypothesis that alcohol problems and PTSD symptom severity would interact and be positively associated with indicators from these three domains. High-risk emerging adults from North America (Study 1, n = 1,311, Mage = 22.13) and general community adults from Canada (Study 2, n = 1,506, Mage = 36.80) completed measures of alcohol problems, PTSD symptoms, delay discounting, alcohol demand, and proportionate alcohol-related reinforcement. Across studies, regression analyses revealed significant main effects of alcohol problems and PTSD symptoms in relation to selected reinforcer pathology indicators, but no significant interactions were present for delay discounting or proportionate alcohol-related reinforcement. Interactions were observed for alcohol consumption at $0 (intensity) and the rate of change in consumption across the demand curve (elasticity; Study 1) and for elasticity and maximum alcohol expenditure (Omax; Study 2), but not in the predicted directions. Higher synergistic severity was associated with lower alcohol reinforcing value in each case. These findings reveal expected relations between reinforcer pathology indicators and both alcohol problems and PTSD symptomatology in general but did not support the hypothesized synergistic relationship. The relation between alcohol problems and PTSD is more complex than predicted by existing extensions of the reinforcer pathology model, warranting further investigation. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

对酗酒问题和创伤后应激综合症的行为经济学分析:来自高风险青少年和普通社区成年人的研究结果。
根据行为经济强化物病理学模型的理论,酗酒问题受到延迟折扣过高、酒精强化物价值过高以及无酒精活动强化物价值过低的影响。本研究将这一理论延伸到酗酒问题与创伤后应激障碍(PTSD)的共存问题中,检验了酗酒问题与创伤后应激障碍症状严重程度相互作用并与这三个领域的指标呈正相关的假设。来自北美的高风险新成人(研究 1,n = 1,311 人,Mage = 22.13)和来自加拿大的普通社区成人(研究 2,n = 1,506 人,Mage = 36.80)完成了酒精问题、创伤后应激障碍症状、延迟折扣、酒精需求和酒精相关强化比例的测量。在所有研究中,回归分析表明,酒精问题和创伤后应激障碍症状与所选强化物病理指标之间存在显著的主效应,但延迟折现或酒精相关强化比例之间不存在显著的交互作用。在0美元的酒精消耗量(强度)和整个需求曲线的消耗量变化率(弹性;研究1)以及弹性和最大酒精消耗量(Omax;研究2)方面观察到了交互作用,但不是预测的方向。在每种情况下,协同严重程度越高,酒精强化价值越低。这些发现揭示了强化物病理指标与一般酒精问题和创伤后应激障碍症状之间的预期关系,但不支持假设的协同关系。酒精问题与创伤后应激障碍之间的关系比强化物病理学模型现有的扩展预测更为复杂,值得进一步研究。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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来源期刊
CiteScore
4.20
自引率
8.70%
发文量
164
审稿时长
6-12 weeks
期刊介绍: Experimental and Clinical Psychopharmacology publishes advances in translational and interdisciplinary research on psychopharmacology, broadly defined, and/or substance abuse.
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