Room-temperature mL-to-μL quantitative liquid concentration device for cyclone flow

IF 1.8 4区化学 Q3 CHEMISTRY, ANALYTICAL

Analytical Sciences Pub Date : 2024-08-30 DOI:10.1007/s44211-024-00654-z

Hidekatsu Tazawa, Kazuma Mawatari

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引用次数: 0

Abstract

Highly sensitive quantitative analysis of liquids is required in various fields. Analytical instruments and devices such as chromatography, spectroscopic analysis, DNA sequencers, immunoassay, mass spectrometry, and microfluidic devices are utilized for this purpose. Typically, the sample volume is at the milliliter scale, while the analysis volume is at the microliter scale. Consequently, most of the sample is discarded. Therefore, a universal volume interface is required to quantitatively concentrate samples from milliliter to microliter volume. This study introduces a liquid quantitative function to the cyclone concentration method using a millimeter-scale channel, which is highly suitable for controlling liquids at the microliter scale due to its high fluidic resistance against cyclone flow. This method enables the effective control of liquid concentration by cyclone flow. The optimum channel structure is investigated, and a 33-fold concentration of aqueous solutions is demonstrated. Finally, the concentration device is applied to measure molybdenum ions in a river.

Graphical abstract

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用于旋流的室温毫升至微升定量液体浓缩装置。

各个领域都需要对液体进行高灵敏度的定量分析。分析仪器和设备，如色谱法、光谱分析、DNA 测序仪、免疫测定、质谱法和微流体设备等，均可用于此目的。通常情况下，样品量为毫升级，而分析量为微升级。因此，大部分样品会被丢弃。因此，需要一个通用的体积接口，将样品从毫升体积定量浓缩到微升体积。本研究利用毫米级通道为旋流浓缩法引入了液体定量功能，由于毫米级通道对旋流的流体阻力大，因此非常适合控制微升量级的液体。这种方法可以通过旋流有效控制液体浓度。对最佳通道结构进行了研究，并展示了水溶液 33 倍的浓缩效果。最后，该浓缩装置被用于测量河流中的钼离子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Analytical Sciences 化学-分析化学

CiteScore

2.90

自引率

18.80%

发文量

232

审稿时长

1 months

期刊介绍： Analytical Sciences is an international journal published monthly by The Japan Society for Analytical Chemistry. The journal publishes papers on all aspects of the theory and practice of analytical sciences, including fundamental and applied, inorganic and organic, wet chemical and instrumental methods. This publication is supported in part by the Grant-in-Aid for Publication of Scientific Research Result of the Japanese Ministry of Education, Culture, Sports, Science and Technology.