Efficacy of acupuncture on drinkers with chronic prostatitis / chronic pelvic pain syndrome: secondary analysis of a randomized clinical trial.

IF 2.4 3区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture in Medicine Pub Date : 2024-09-01 DOI:10.1177/09645284241274158

Lili Zhu, Yuanjie Sun, Shiyan Yan, Xiaoxu Liu, Xinlu Wang, Zhishun Liu

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引用次数: 0

Abstract

Objective: To evaluate the efficacy of acupuncture in drinkers with chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS).

Methods: We conducted a secondary analysis of a randomized controlled trial across multiple centers, involving 224 drinkers. Patients received either acupuncture or sham acupuncture treatment. The primary outcome was the proportion of responders, defined as participants who had a reduction of 6 points or more from baseline in the National Institute of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) total score at weeks 8 and 32. Secondary outcomes measures included the Global Response Assessment (GRA), International Prostate Symptom Score (IPSS) and International Index of Erectile Function 5 (IIEF-5).

Results: One hundred and twelve drinkers were included in each group (n = 224 in total). The proportion of responders in terms of NIH-CPSI was 58.9% versus 40.3% in the acupuncture group (AG) and sham acupuncture group (SAG), respectively, with a statistically significant difference of 18.6% (p = 0.002) at week 8. Higher proportions of responders with respect to NIH-CPSI (p < 0.001 at week 32) and GRA (p < 0.001 at week 8 and p = 0.01 at week 32) were observed in the AG compared with the SAG. No between-group differences were found in the changes in IPSS at any assessment time point. Changes in IIEF-5 score were significantly higher in the AG than in the SAG at weeks 20 and 32, while the difference was not statistically significant at week 8.

Conclusion: Acupuncture appeared to alleviate the symptoms of pain among drinkers with CP/CPPS and improve their quality of life, but had no demonstrable effect on urinary tract symptoms or erectile function among these patients.

Trial registration number: NCT03213938 (ClinicalTrials.gov).

查看原文本刊更多论文

针灸对慢性前列腺炎/慢性盆腔疼痛综合征饮酒者的疗效：随机临床试验的二次分析。

目的评估针灸对慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）饮酒者的疗效：我们在多个中心对一项涉及 224 名饮酒者的随机对照试验进行了二次分析。患者接受了针灸或假针灸治疗。主要结果是应答者的比例，即在第 8 周和第 32 周时，美国国立卫生研究院-慢性前列腺炎症状指数（NIH-CPSI）总分比基线降低 6 分或更多的参与者。次要结果指标包括全球反应评估（GRA）、国际前列腺症状评分（IPSS）和国际勃起功能指数5（IIEF-5）：结果：每组包括 112 名饮酒者（共 224 人）。针灸组（AG）和假针灸组（SAG）的NIH-CPSI应答者比例分别为58.9%和40.3%，在第8周时差异为18.6%（P = 0.002），具有显著统计学意义。与假针灸组相比，针灸组的 NIH-CPSI 反应者比例更高（第 32 周时 p p = 0.01）。在任何评估时间点，IPSS 的变化均未发现组间差异。在第 20 周和第 32 周，AG 组的 IIEF-5 评分变化明显高于 SAG 组，而在第 8 周，差异无统计学意义：针灸似乎可以减轻 CP/CPPS 饮酒者的疼痛症状，改善他们的生活质量，但对这些患者的尿路症状或勃起功能没有明显效果：NCT03213938（ClinicalTrials.gov）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acupuncture in Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

4.70

自引率

4.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Acupuncture in Medicine aims to promote the scientific understanding of acupuncture and related treatments by publishing scientific investigations of their effectiveness and modes of action as well as articles on their use in health services and clinical practice. Acupuncture in Medicine uses the Western understanding of neurophysiology and anatomy to interpret the effects of acupuncture.