Chemophenetics of the subtribe Cercidinae (Fabaceae, Cercideae)

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-08-29 DOI:10.1016/j.bse.2024.104890

Mohaddeseh Moghaddam, Christian Zidorn

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Abstract

The genera Adenolobus, Cercis and Griffonia are closely related and classified within the subtribe Cercidinae of the Fabaceae family. Since no information exists on the secondary metabolites of the genus Adenolobus, this review focuses on the phytochemistry of Cercis and Griffonia. The genus Cercis is a source of interesting specialized metabolites including 82 phenolic compounds comprising 51 flavonoids, ten terpenoids, three cyanogenic glycosides, 54 volatile compounds, and some compounds from other compound classes. In the genus Griffonia, G. simplicifolia has been traditionally used for a variety of medicinal purposes, and research is mainly focused on this species. This review discusses the chemical structures of nine alkaloids reported from G. simplicifolia and compounds isolated from the genus Cercis along with their chemophenetic analysis. Finally, the review briefly mentions research gaps and potential directions for future investigations.

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ercidinae亚族（豆科，ercideae）的化学遗传学

Adenolobus属、Cercis属和Griffonia属关系密切，属于豆科Cercidinae亚族。由于没有关于 Adenolobus 属次生代谢物的信息，本综述主要关注 Cercis 和 Griffonia 的植物化学。Cercis 属是有趣的特殊代谢物的来源，包括 82 种酚类化合物，其中有 51 种黄酮类化合物、10 种萜类化合物、3 种氰甙类化合物、54 种挥发性化合物以及其他化合物类别中的一些化合物。在 Griffonia 属中，G. simplicifolia 在传统上被用于多种药用目的，研究主要集中在这一物种上。本综述讨论了从 G. simplicifolia 中报告的九种生物碱的化学结构，以及从 Cercis 属中分离的化合物及其化学遗传学分析。最后，综述简要介绍了研究空白和未来研究的潜在方向。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.