Association of epicardial adipose tissue density with postoperative atrial fibrillation after isolated aortic valve replacement

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
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引用次数: 0

Abstract

Backgrounds

It is well known that epicardial adipose tissue (EAT) is associated with the development of atrial fibrillation (AF). The aim of this study was to investigate whether EAT density (EAT-d) is associated with the development of new-onset atrial fibrillation (POAF) after aortic valve replacement (AVR).

Methods

We retrospectively studied 143 patients who underwent simple AVR at Department of Cardiovascular Surgery of the General Hospital of Northern Theater Command between June 2020 to August 2023. All patients received cardiac coronary artery computed tomography (CT) before surgery. EAT-d, EAT volume and EAT volume index (EATVI) were quantitatively measured and analysed using EAT analysis software (TIMESlicePro). POAF was detected by 7-day Holter monitoring.

Results

Of 143 patients undergoing AVR, 55 patients (38.46 %) developed POAF after surgery. Male patients and patients who had elder age or smoking history were more likely to develop POAF. On univariable analysis, patients developed POAF had significantly more EAT-d (−79.19(−83.91, −74.69) vs. −81.54(−87.16, −76.76); P = 0.043) and EATVI (4.14(3.32,5.03) vs. 3.90(2.70,4.51); P = 0.043) than patients without POAF. On multivariable analysis, EAT-d and age were independent risk factors for POAF (odds ratio (OR): 1.186, 95 % confidence interval (CI): 1.062–1.324, P = 0.002; OR: 1.119, 95 %CI: 1.055–1.187, P < 0.001). Furthermore, EAT-d was significantly associated with age. Furthermore, EAT-d was associated with cardiac structure changes, such as cardiac left ventricular end-diastolic, left ventricular end-systolic volumes and NT-proBNP before surgery.

Conclusion

EAT-d and age are independent predictors of POAF after simple AVR. EAT-d was related with age.

孤立主动脉瓣置换术后心外膜脂肪组织密度与心房颤动的关系
背景众所周知,心外膜脂肪组织(EAT)与心房颤动(AF)的发生有关。本研究旨在探讨 EAT 密度(EAT-d)是否与主动脉瓣置换术(AVR)后新发心房颤动(POAF)的发生有关。方法我们回顾性研究了 2020 年 6 月至 2023 年 8 月期间在北部战区司令部总医院心血管外科接受单纯 AVR 的 143 例患者。所有患者术前均接受了心脏冠状动脉计算机断层扫描(CT)。使用EAT分析软件(TIMESlicePro)对EAT-d、EAT体积和EAT体积指数(EATVI)进行定量测量和分析。结果 在接受 AVR 的 143 名患者中,55 名患者(38.46%)在术后出现 POAF。男性患者、年龄较大或有吸烟史的患者更容易出现 POAF。单变量分析显示,发生 POAF 的患者的 EAT-d (-79.19(-83.91, -74.69) vs. -81.54(-87.16, -76.76); P = 0.043) 和 EATVI (4.14(3.32,5.03) vs. 3.90(2.70,4.51); P = 0.043) 明显高于未发生 POAF 的患者。多变量分析显示,EAT-d 和年龄是 POAF 的独立危险因素(几率比(OR):1.186,95 % 置信区间(CI):1.062-1.324,P = 0.002;OR:1.119,95 %CI:1.055-1.187,P <0.001)。此外,EAT-d 与年龄明显相关。结论 EAT-d 和年龄是单纯 AVR 术后 POAF 的独立预测因素。EAT-d与年龄有关。
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来源期刊
IJC Heart and Vasculature
IJC Heart and Vasculature Medicine-Cardiology and Cardiovascular Medicine
CiteScore
4.90
自引率
10.30%
发文量
216
审稿时长
56 days
期刊介绍: IJC Heart & Vasculature is an online-only, open-access journal dedicated to publishing original articles and reviews (also Editorials and Letters to the Editor) which report on structural and functional cardiovascular pathology, with an emphasis on imaging and disease pathophysiology. Articles must be authentic, educational, clinically relevant, and original in their content and scientific approach. IJC Heart & Vasculature requires the highest standards of scientific integrity in order to promote reliable, reproducible and verifiable research findings. All authors are advised to consult the Principles of Ethical Publishing in the International Journal of Cardiology before submitting a manuscript. Submission of a manuscript to this journal gives the publisher the right to publish that paper if it is accepted. Manuscripts may be edited to improve clarity and expression.
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