Outcomes after open posterior component separation via transversus abdominis release (TAR) for incisional hernia repair. A systematic review and meta-analysis.

IF 2.6 2区 医学 Q1 SURGERY
Hernia Pub Date : 2024-12-01 Epub Date: 2024-08-27 DOI:10.1007/s10029-024-03142-5
Emmanuel E Sadava, Francisco Laxague, Agustin C Valinoti, Cristian A Angeramo, Francisco Schlottmann
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引用次数: 0

Abstract

Purpose: Given its potential advantages, open Transversus Abdominis Release (oTAR) has been proposed as a durable solution for complex AWR. However, its applicability in different scenarios remains uncertain. We aimed to analyze the current available evidence and determine surgical outcomes after oTAR.

Methods: We performed a systematic electronic search on oTAR in PubMed/Medline, Embase, and Cochrane Central Register of Controlled Trials databases. Postoperative morbidity and recurrence rates were included as primary endpoints and Quality of life (QoL) was included as secondary endpoint. A random-effect model was used to generate a pooled proportion with 95% confidence interval (CI) between all studies.

Results: A total of 22 studies with 4,910 patients undergoing oTAR were included for analysis. Mean hernia defect and mesh area were 394 (140-622) cm2 and 1065 (557-2206) cm2, respectively. Mean follow-up was 19.7 (1-32) months. The weighted pooled proportion of recurrence, overall morbidity, surgical site occurrences (SSO), surgical site infection (SSI), surgical site occurrences requiring procedural intervention (SSOPI), major morbidity and mortality were: 6% (95% CI, 3-10%), 34% (95% CI, 26-43%), 22% (95% CI, 16-29%), 11% (95% CI, 8-16%), 4% (95% CI, 3-7%), 6% (95% CI, 4-10%) and 1% (95% CI, 1-2%), respectively. A significant improvement in QoL after oTAR was reported among studies.

Conclusion: Open TAR is an effective technique for complex ventral hernias as it is associated with low recurrence rate and a significant improvement in QoL. However, the relatively high morbidity rates observed emphasize the necessity of further patients' selection and optimization to improve outcomes.

Abstract Image

切口疝修补术中通过腹横肌松解术(TAR)进行开放式后方组件分离后的疗效。系统回顾和荟萃分析。
目的:鉴于其潜在的优势,开放式腹横肌松解术(oTAR)已被提议作为复杂 AWR 的持久解决方案。然而,其在不同情况下的适用性仍不确定。我们旨在分析当前可用的证据,并确定 oTAR 后的手术效果:我们在 PubMed/Medline、Embase 和 Cochrane Central Register of Controlled Trials 数据库中对 oTAR 进行了系统的电子检索。将术后发病率和复发率作为主要终点,将生活质量(QoL)作为次要终点。采用随机效应模型得出所有研究的汇总比例及 95% 置信区间 (CI):共纳入了 22 项研究,对 4910 名接受 oTAR 的患者进行了分析。平均疝缺损和网片面积分别为 394 (140-622) 平方厘米和 1065 (557-2206) 平方厘米。平均随访时间为 19.7 (1-32) 个月。复发率、总发病率、手术部位发生率(SSO)、手术部位感染率(SSI)、需要手术干预的手术部位发生率(SSOPI)、主要发病率和死亡率的加权汇总比例分别为死亡率分别为:6%(95% CI,3-10%)、34%(95% CI,26-43%)、22%(95% CI,16-29%)、11%(95% CI,8-16%)、4%(95% CI,3-7%)、6%(95% CI,4-10%)和 1%(95% CI,1-2%)。结论:开放式 TAR 是一种有效的乳腺癌治疗技术:结论:开放式 TAR 是一种治疗复杂腹股沟疝的有效技术,因为它的复发率低,生活质量明显改善。结论:开放式 TAR 是治疗复杂腹股沟疝的有效技术,因为复发率低且 QoL 明显改善。然而,观察到的相对较高的发病率强调了进一步选择和优化患者以改善疗效的必要性。
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来源期刊
Hernia
Hernia SURGERY-
CiteScore
4.90
自引率
26.10%
发文量
171
审稿时长
4-8 weeks
期刊介绍: Hernia was founded in 1997 by Jean P. Chevrel with the purpose of promoting clinical studies and basic research as they apply to groin hernias and the abdominal wall . Since that time, a true revolution in the field of hernia studies has transformed the field from a ”simple” disease to one that is very specialized. While the majority of surgeries for primary inguinal and abdominal wall hernia are performed in hospitals worldwide, complex situations such as multi recurrences, complications, abdominal wall reconstructions and others are being studied and treated in specialist centers. As a result, major institutions and societies are creating specific parameters and criteria to better address the complexities of hernia surgery. Hernia is a journal written by surgeons who have made abdominal wall surgery their specific field of interest, but we will consider publishing content from any surgeon who wishes to improve the science of this field. The Journal aims to ensure that hernia surgery is safer and easier for surgeons as well as patients, and provides a forum to all surgeons in the exchange of new ideas, results, and important research that is the basis of professional activity.
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