Fabrication and Characterization of Brain Tissue Phantoms Using Agarose Gels for Ultraviolet Vision Systems.

IF 5 3区 化学 Q1 POLYMER SCIENCE
Gels Pub Date : 2024-08-20 DOI:10.3390/gels10080540
Luis M Vidal-Flores, Miguel Reyes-Alberto, Efraín Albor-Ramírez, César F Domínguez-Velasco, Enoch Gutierrez-Herrera, Miguel A Padilla-Castañeda
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引用次数: 0

Abstract

Recreating cerebral tissue using a tissue-mimicking phantom is valuable because it provides a tool for studying physiological and biological processes related to tissues without the necessity of performing the study directly in the tissue or even in a patient. The reproduction of the optical properties allows investigation in areas such as imaging, optics, and ultrasound, among others. This paper presents a methodology for manufacturing agarose-based phantoms that mimic the optical characteristics of brain tissue using scattering and absorbing agents and proposes combinations of these agents to recreate the healthy brain tissue optical coefficients within the wavelength range of 350 to 500 nm. The results of the characterization of the manufactured phantoms propose ideal combinations of the used materials for their use in controlled environment experiments in the UV range, following a cost-effective methodology.

使用琼脂糖凝胶制作和表征用于紫外线视觉系统的脑组织模型。
使用组织模拟模型再现脑组织是非常有价值的,因为它为研究与组织相关的生理和生物过程提供了一种工具,而无需直接在组织中甚至在病人身上进行研究。光学特性的再现可用于成像、光学和超声等领域的研究。本文介绍了一种利用散射剂和吸收剂制造琼脂糖基模型的方法,该模型可模拟脑组织的光学特性,并提出了这些散射剂和吸收剂的组合,以在 350 至 500 纳米波长范围内再现健康脑组织的光学系数。对制造的模型进行表征的结果提出了理想的材料组合,以便在紫外线范围内的受控环境实验中使用,并采用了具有成本效益的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gels
Gels POLYMER SCIENCE-
CiteScore
4.70
自引率
19.60%
发文量
707
审稿时长
11 weeks
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