Nonablative Fractional Diode Laser Resurfacing (1440 nm and 1927 nm) for Photoaged Skin.

IF 2.5 3区医学 Q2 DERMATOLOGY

Dermatologic Surgery Pub Date : 2024-08-27 DOI:10.1097/DSS.0000000000004379

Kristel D Polder, Paul M Friedman, Jill Feetham, Jessica Gower, Tina Lin, Abby Jacobson

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引用次数: 0

Abstract

Background: Nonablative lasers treat photoaged skin and stimulate new collagen formation while sparing epidermal damage.

Objective: To evaluate the effectiveness and safety of nonablative fractional diode combination laser skin resurfacing treatment (1440 and 1927 nm) in mild-to-moderate photoaged skin.

Materials and methods: The entire face was treated with both 1440-nm and 1927-nm wavelengths per treatment, with a total of 4 treatments spaced 1 month apart. Follow-up occurred at 1 and 3 months post-treatment. Outcomes were improvement in the appearance of ≥1 measure of photodamage (rhytides, skin texture, dyschromia/pigment, skin radiance, pore size, and overall appearance) at the 3-month (primary) and 1-month (secondary) follow-up visits. Safety was monitored throughout the study.

Results: Participants (N = 28; 89% female; mean age, 40 years) experienced significant mean improvement from baseline in all measures of photodamage with combination laser treatment at 1 and 3 months post-treatment (all p < .001). No serious adverse events occurred. Post-treatment erythema and edema were minimal, and pain levels remained consistent throughout treatment. Most participants (96.4%) considered their overall appearance as improved and expressed satisfaction with treatment outcomes.

Conclusion: Nonablative combination laser skin resurfacing treatment was well tolerated and significantly improved measures of photodamage in photoaged skin across diverse skin types.

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用于光老化皮肤的非烧蚀点阵二极管激光换肤术（1440 纳米和 1927 纳米）。

背景：非剥脱激光治疗光老化皮肤，刺激新胶原蛋白的形成，同时避免表皮损伤：评估非剥脱点阵二极管组合激光焕肤治疗（1440 和 1927 纳米）对轻度至中度光老化皮肤的有效性和安全性：对整个面部进行治疗，每次治疗同时使用 1440 纳米和 1927 纳米波长，共进行 4 次治疗，每次治疗间隔 1 个月。治疗后 1 个月和 3 个月进行随访。结果是在 3 个月（主要）和 1 个月（次要）随访时，≥1 项光损伤指标（褶皱、肤质、色素沉着/色斑、皮肤光泽度、毛孔大小和整体外观）的改善情况。在整个研究过程中对安全性进行监测：参加者（28 人；89% 为女性；平均年龄 40 岁）在治疗后 1 个月和 3 个月接受联合激光治疗后，所有光损伤指标的平均值都比基线值有显著改善（P 均小于 0.001）。无严重不良反应发生。治疗后的红斑和水肿非常轻微，疼痛程度在整个治疗过程中保持一致。大多数参与者（96.4%）认为他们的整体外观得到了改善，并对治疗效果表示满意：结论：非烧蚀联合激光换肤治疗的耐受性良好，能显著改善不同肤质的光老化皮肤的光损伤程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.