Characterization of an At-Risk Population for Nonalcoholic Fatty Liver Disease (NAFLD) in a Primary Care Setting Along the U.S.-Mexico Border.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-08-27 DOI:10.1177/10436596241271265

Lindsay Spitz, Stefan Saadiq, Navkiran K Shokar, Marc J Zuckerman, Nancy A Casner, Roy Valenzuela, Jennifer J Salinas

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Abstract

Introduction: This study aimed to determine the burden of suspected nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) in a predominantly Hispanic patient population and explore the utility of the American Gastroenterological Association's NAFLD Clinical Care Pathway (CCP).

Methodology: Electronic medical records (n = 223) were used to divide patients into risk groups based on the amount of metabolic risk factors they presented, diabetic status, or if they presented other liver diseases. Fribosis-4 (FIB-4) scores were used to determine the risk for advanced fibrosis.

Results: Most patients (83.8%) were considered at risk for NAFLD based on CCP criteria, and about a third of patients (33.2%) were found to be at indeterminate (n = 60; 26.9%) or high risk (n = 14; 6.3%) for advanced fibrosis. Most indeterminate-risk patients (78.3%) were not referred for liver imaging.

Discussion: This study demonstrates the potential of the CCP as a corrective tool that could help to better identify and screen patients at risk for NAFLD.

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美国-墨西哥边境初级医疗机构中非酒精性脂肪肝 (NAFLD) 高危人群的特征。

简介：本研究旨在确定以西班牙裔患者为主的人群中疑似非酒精性脂肪肝（NAFLD）和非酒精性脂肪性肝炎（NASH）的负担，并探索美国胃肠病学协会非酒精性脂肪肝临床护理路径（CCP）的实用性：方法：利用电子病历（n = 223），根据患者的代谢风险因素、糖尿病状态或是否患有其他肝脏疾病，将患者分为不同的风险组。Fribosis-4（FIB-4）评分用于确定晚期纤维化的风险：根据CCP标准，大多数患者（83.8%）被认为存在非酒精性脂肪肝风险，约三分之一的患者（33.2%）被认为存在晚期纤维化的不确定风险（60人；26.9%）或高风险（14人；6.3%）。大多数不确定风险的患者（78.3%）没有转诊进行肝脏成像检查：本研究表明，CCP 作为一种纠正工具，可帮助更好地识别和筛查非酒精性脂肪肝高危患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.