RETRACTION: FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells

IF 3 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
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引用次数: 0

Abstract

RETRACTION: Y. Zhou, L. Wei, H. Zhang, Q. Dai, Z. Li, B. Yu, et al., “FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells,” Journal of Cellular Biochemistry 116, no. 8 (2015): 1624–1637, https://doi.org/10.1002/jcb.25118.

The above article, published online on 3 February 2015 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Christian Behl; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties related to the data presented in the article. Specifically, duplication of Western Blot images has been detected across Figures 5D and 6A; and 5B, 6B and 6I. Furthermore, inappropriate post-acquisition modifications have been detected within Figure 4B and 4F, and image elements in Figure 4B and 4E were found to have been previously published by the same author group in a different scientific context. The authors were unable to provide the relative raw data upon request. Finally, the cell lines used in this study (BGC-823 and MGC-803) have been reported as contaminated [1-4]. Therefore, retraction has been agreed upon as the editors consider the conclusions of this article to be invalid. The authors have been informed of the decision of retraction but unavailable for a final confirmation.

回归:FV-429 通过 ROS 介导的 ERK2 核转移和 p53 激活诱导胃癌细胞凋亡
撤回:Y. Zhou, L. Wei, H. Zhang, Q. Dai, Z. Li, B. Yu, et al., "FV-429 Induced Apoptosis Through ROS-Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells," Journal of Cellular Biochemistry 116, no. 8 (2015): 1624-1637, https://doi.org/10.1002/jcb.25118.上述文章于 2015 年 2 月 3 日在线发表于 Wiley Online Library (wileyonlinelibrary.com),经期刊主编 Christian Behl 和 Wiley Periodicals LLC 协议,该文章已被撤回。同意撤稿的原因是第三方对文章中提供的数据提出了疑虑。具体来说,在图 5D 和 6A 以及图 5B、6B 和 6I 中发现了 Western Blot 图像的重复。此外,在图 4B 和图 4F 中发现了不恰当的采集后修改,图 4B 和图 4E 中的图像元素被发现之前已由同一作者小组在不同的科学背景下发表过。作者无法应要求提供相关原始数据。最后,本研究中使用的细胞系(BGC-823 和 MGC-803)已被报道为受到污染[1-4]。因此,由于编辑认为这篇文章的结论无效,同意撤回。作者已被告知撤稿决定,但尚未得到最终确认。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of cellular biochemistry
Journal of cellular biochemistry 生物-生化与分子生物学
CiteScore
9.90
自引率
0.00%
发文量
164
审稿时长
1 months
期刊介绍: The Journal of Cellular Biochemistry publishes descriptions of original research in which complex cellular, pathogenic, clinical, or animal model systems are studied by biochemical, molecular, genetic, epigenetic or quantitative ultrastructural approaches. Submission of papers reporting genomic, proteomic, bioinformatics and systems biology approaches to identify and characterize parameters of biological control in a cellular context are encouraged. The areas covered include, but are not restricted to, conditions, agents, regulatory networks, or differentiation states that influence structure, cell cycle & growth control, structure-function relationships.
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