Association between bone age maturity and childhood adiposity

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity Pub Date : 2024-08-26 DOI:10.1111/ijpo.13166

Ana Gabriela Chávez-Vázquez, Miguel Klünder-Klünder, Desiree Lopez-Gonzalez, Jenny Vilchis-Gil, América Liliana Miranda-Lora

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引用次数: 0

Abstract

Background

Evidence shows that overweight and obesity are associated with advanced bone age (BA).

Objective

To analyse the effect of adiposity on BA among Mexican children.

Methods

This cross-sectional study included 902 children (5–18 years old). Anthropometric measurements, dual-energy X-ray absorptiometry (DXA) and automated hand X-ray-based BA measurements were obtained. BA curves of children stratified by sex and age were created based on nutritional status. We also calculated odds ratios for advanced BA associated with the body mass index (BMI), waist/height ratio and adiposity estimated using DXA (total and truncal fat mass).

Results

Participants with overweight/obesity by BMI (SDS ≥1) advanced earlier in BA than did normal weight participants (6.0 vs. 12.0 years in boys and 6.0 vs. 10.3 in girls, p < 0.01); similarly, participants with a greater body fat percentage (SDS ≥1) exhibited earlier advanced BA (7.5 vs. 10.0 years in boys and 6.0 vs. 9.6 in girls, p < 0.01). Differences were also observed according to the waist/height ratio and truncal fat. Children with a BMI or DXA SDS ≥1 had greater odds of presenting an advanced BA of more than 1 year (OR 1.79–3.55, p < 0.05).

Conclusions

Increased adiposity in children, mainly in boys, is associated with advanced BA at earlier ages.

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骨龄成熟度与儿童肥胖之间的关系。

背景：有证据表明，超重和肥胖与骨龄（BA）增大有关：有证据表明，超重和肥胖与骨龄（BA）提前有关：分析肥胖对墨西哥儿童骨龄的影响：这项横断面研究包括 902 名儿童（5-18 岁）。方法：这项横断面研究纳入了 902 名儿童（5-18 岁），对他们进行了人体测量、双能量 X 射线吸收测量（DXA）和基于手部 X 射线的自动 BA 测量。根据营养状况绘制了按性别和年龄分层的儿童 BA 曲线。我们还计算了晚期 BA 与体重指数 (BMI)、腰围/身高比和 DXA 估计的脂肪含量（总脂肪量和躯干脂肪量）相关的几率比：结果：体重指数（BMI）超重/肥胖（SDS ≥1）的参与者比体重正常的参与者更早进入 BA 阶段（男孩为 6.0 岁对 12.0 岁，女孩为 6.0 岁对 10.3 岁，P儿童（主要是男孩）脂肪含量的增加与 BA 早熟有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.