Long-term outcomes of minimally invasive concomitant mitral and tricuspid valve surgery with surgical ablation.

0 CARDIAC & CARDIOVASCULAR SYSTEMS
Sungsil Yoon, Kitae Kim, Jae Suk Yoo, Joon Bum Kim, Cheol Hyun Chung, Sung-Ho Jung
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Abstract

Objectives: We compared the outcomes of a right mini-thoracotomy (RMT) versus those of a sternotomy for concomitant mitral and tricuspid valve surgery and surgical ablation.

Methods: We analysed patients who underwent concomitant mitral and tricuspid valve surgery and surgical ablation at a single institution (mean follow-up: 7 years) after propensity score matching. The primary and secondary outcomes were all-cause death, composite major adverse events (including stroke, reoperation, readmission, permanent pacemaker insertion) and recurrence of atrial fibrillation (A-fib). A subgroup analysis was performed.

Results: A total of 797 procedures (mean age: 61.6 years; RMT: 45.2%; female: 66.5%; mitral valve repair: 33.6%) were done; 267 pairs were matched. The 5- and 10-year overall survival in the matched cohort was 92.7% and 86.9% for the RMT group and 92.1% and 83.1% for the sternotomy group (P = 0.879). Significant differences were not observed in major adverse events (P = 0.273; hazard ratio: 0.76) and A-fib recurrence (P = 0.080; hazard ratio: 0.72). The RMT group had lower rates of postoperative low cardiac output syndrome (P = 0.019) and acute renal failure (P = 0.003). Atrial fibrillation high-risk factors (including long-standing A-fib, enlarged left atrium, old age) exhibited significant interactions (P for interaction = 0.002) with the approach regarding A-fib recurrence.

Conclusions: In this study, an RMT exhibited no significant differences in long-term outcomes compared to a sternotomy, but it could remain a clinically reasonable option. Patients with a high risk of A-fib may have favourable ablation outcomes with a sternotomy.

二尖瓣和三尖瓣同期微创手术与手术消融的长期疗效。
目的我们比较了二尖瓣和三尖瓣同时手术和手术消融时右小开胸(mini-thoracotomy)与胸骨切开术的结果:我们分析了在单一机构接受二尖瓣和三尖瓣同期手术和手术消融的患者(平均随访时间:7 年),并进行了倾向评分匹配。主要和次要结果为全因死亡、复合主要不良事件(包括中风、再次手术、再次入院、植入永久起搏器)和心房颤动复发。进行了分组分析:33.6%),267对进行了配对。配对队列的5年和10年总生存率分别为:右小胸切口组92.7%和86.9%,胸骨切开组92.1%和83.1%(P = 0.879)。在主要不良事件(p = 0.273,危险比:0.76)和心房颤动复发(p = 0.080,危险比:0.72)方面未观察到显著差异。右小胸廓切开术组术后低心排血量综合征(p = 0.019)和急性肾衰竭(p = 0.003)发生率较低。心房颤动高危因素(包括长期存在的心房颤动、左心房扩大、高龄)与心房颤动复发的方法有显著的交互作用(交互作用的 p = 0.002):结论:在本研究中,与胸骨切开术相比,右小胸廓切开术在长期预后方面无明显差异,但在临床上仍是一种合理的选择。具有心房颤动高危因素的患者采用胸骨切开术可能会获得较好的消融效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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