Efficacy and safety of Adrenaline-augmented subconjunctival anesthesia in phacoemulsification: A randomized controlled trial.

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
European Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-08-25 DOI:10.1177/11206721241272198
Sandepan Bandopadhyay, Deependra Kumar Sinha, Vijay K Sharma, Bhavaraj Veerabhadhra Rao, Neeraj Sharma, Vipin Rana
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引用次数: 0

Abstract

Background/objectives: Cataract surgery, particularly phacoemulsification, has evolved significantly, benefiting millions worldwide. The choice of anesthesia technique impacts patient comfort and procedural efficacy. Subconjunctival anesthesia has emerged as an attractive alternative due to its potential to provide effective pain relief and surgeon comfort during surgery. A different aspect of this study is the inclusion of 1:100,000 adrenaline in 2% lignocaine for subconjunctival anesthesia, which has not been previously studied.

Subjects/methods: A prospective, randomised, comparative study involving 196 eyes evaluated the safety and efficacy of subconjunctival anesthesia in phacoemulsification surgery. Pain scores during surgery and one hour post-surgery, surgeon discomfort, postoperative corneal clarity, complications, and additional anesthesia requirement were assessed. Statistical analysis employed descriptive statistics, t-tests, chi-squared tests, and correlations.

Results: Subconjunctival anesthesia significantly lowered pain scores during surgery (p < 0.001) and one hour post-surgery (p < 0.001) compared to topical anesthesia. Surgeon discomfort was notably reduced with subconjunctival anesthesia (p < 0.001). Subconjunctival hemorrhage (p = 0.012) and redness (p = 0.024) were more prevalent postoperatively. No significant difference was observed in intraoperative complications (p = 0.573) or postoperative corneal clarity (p = 0.347).

Conclusion: Subconjunctival anesthesia, with the inclusion of 1:100,000 adrenaline in 2% lignocaine, provides effective pain relief and reduces surgeon discomfort during phacoemulsification surgery. The addition of adrenaline extends anesthesia duration. While immediate postoperative effects exist, subconjunctival anesthesia holds promise for enhanced patient comfort and procedural efficiency. Further research is needed to validate its long-term benefits and broader implications in evolving ophthalmic surgical practices.

肾上腺素增强结膜下麻醉在超声乳化术中的有效性和安全性:随机对照试验。
背景/目的:白内障手术,尤其是超声乳化术,已经有了长足的发展,使全球数百万人受益。麻醉技术的选择会影响患者的舒适度和手术效果。结膜下麻醉因其在手术过程中能有效减轻疼痛并使外科医生感到舒适而成为一种有吸引力的选择。本研究的一个不同之处是将 1:100,000 肾上腺素加入 2% 木质素中用于结膜下麻醉,这在以前还没有过研究:一项涉及 196 只眼睛的前瞻性随机比较研究评估了结膜下麻醉在超声乳化手术中的安全性和有效性。研究评估了手术中和手术后一小时内的疼痛评分、外科医生的不适感、术后角膜清晰度、并发症和额外的麻醉需求。统计分析采用了描述性统计、t 检验、卡方检验和相关性检验:结果:结膜下麻醉明显降低了手术中的疼痛评分(p p p = 0.012),术后发红(p = 0.024)的情况更为普遍。术中并发症(p = 0.573)和术后角膜清晰度(p = 0.347)无明显差异:结膜下麻醉在2%木质素中加入1:100,000肾上腺素,可有效缓解疼痛,并减少超声乳化手术中外科医生的不适感。肾上腺素的加入延长了麻醉时间。虽然术后会立即产生影响,但结膜下麻醉有望提高患者的舒适度和手术效率。还需要进一步的研究来验证其长期益处以及对不断发展的眼科手术实践的广泛影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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