Optimizing Colonoscopy Preparation in Autistic Children: A Comparative Study of Hypertonic Sugar Saline and Normal Saline Enemas.

IF 1 4区 医学 Q3 PEDIATRICS
Xinyu Jin, Weisong Sheng, Xinrong Liu, Danrong Zhu
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引用次数: 0

Abstract

Objective: This study evaluates the effectiveness of combining oral polyethylene glycol electrolyte solution with hypertonic sugar saline enema for colonoscopy preparation in autistic children.

Methods: Clinical data of 58 children with autism who underwent fecal bacteria transplantation and transendoscopic enteral tubing (TET) catheterization at the hospital were retrospectively analyzed. Participants were allocated into 2 groups: a control group (26 children) and an observation group (32 children), differentiated by their intestinal preparation protocols. The control group was administered oral polyethylene glycol combined with normal saline enema, whereas the observation group was given oral polyethylene glycol combined with hypertonic sugar saline enema. The Boston Bowel Preparation Scale (BBPS) was used to score intestinal cleanliness. Differences in intestinal cleanliness and colonoscopy duration between the 2 groups were compared.

Results: The group treated with hypertonic sugar saline enema exhibited significantly higher BBPS scores (6.78 ± 0.83) and an intestinal passage rate of 96.86%, which were statistically significant compared with the control group (P < 0.05). In addition, the colonoscopy duration was notably shorter in the observation group (14.03 ± 4.86 minutes) compared with the control group (P < 0.05).

Conclusion: Our findings suggest that an oral polyethylene glycol electrolyte solution combined with a hypertonic sugar saline enema is a more effective preparation method for colonoscopy in autistic children.

优化自闭症儿童结肠镜检查前的准备工作:高渗糖生理盐水和正常生理盐水灌肠的比较研究。
研究目的本研究评估了将聚乙二醇电解质口服液与高渗糖盐水灌肠剂结合用于自闭症儿童结肠镜检查准备的有效性:回顾性分析了在医院接受粪便细菌移植和经内镜肠管(TET)导管术的 58 名自闭症儿童的临床数据。受试者被分为两组:对照组(26 名儿童)和观察组(32 名儿童),按肠道准备方案进行区分。对照组口服聚乙二醇并用生理盐水灌肠,而观察组口服聚乙二醇并用高渗糖生理盐水灌肠。采用波士顿肠道准备量表(BBPS)对肠道清洁度进行评分。比较两组肠道清洁度和结肠镜检查时间的差异:高渗生理盐水灌肠组的 BBPS 评分(6.78 ± 0.83)和肠道通过率(96.86%)明显高于对照组,差异有统计学意义(P < 0.05)。此外,与对照组相比,观察组的结肠镜检查时间明显缩短(14.03 ± 4.86 分钟)(P < 0.05):我们的研究结果表明,口服聚乙二醇电解质溶液与高渗糖盐水灌肠相结合是自闭症儿童结肠镜检查前更有效的准备方法。
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来源期刊
Clinical Pediatrics
Clinical Pediatrics 医学-小儿科
CiteScore
2.10
自引率
6.20%
发文量
189
审稿时长
3-8 weeks
期刊介绍: Clinical Pediatrics (CLP) a peer-reviewed monthly journal, is a must read for the busy pediatrician. CLP contains state-of-the-art, accurate, concise and down-to earth information on practical, everyday child care topics whether they are clinical, scientific, behavioral, educational, or ethical.
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