Language and the Cerebellum: Structural Connectivity to the Eloquent Brain.

IF 3.6 Q1 LINGUISTICS
Neurobiology of Language Pub Date : 2024-08-15 eCollection Date: 2024-01-01 DOI:10.1162/nol_a_00085
Katie R Jobson, Linda J Hoffman, Athanasia Metoki, Haroon Popal, Anthony S Dick, Jamie Reilly, Ingrid R Olson
{"title":"Language and the Cerebellum: Structural Connectivity to the Eloquent Brain.","authors":"Katie R Jobson, Linda J Hoffman, Athanasia Metoki, Haroon Popal, Anthony S Dick, Jamie Reilly, Ingrid R Olson","doi":"10.1162/nol_a_00085","DOIUrl":null,"url":null,"abstract":"<p><p>Neurobiological models of receptive language have focused on the left-hemisphere perisylvian cortex with the assumption that the cerebellum supports peri-linguistic cognitive processes such as verbal working memory. The goal of this study was to identify language-sensitive regions of the cerebellum then map the structural connectivity profile of these regions. Functional imaging data and diffusion-weighted imaging data from the Human Connectome Project (HCP) were analyzed. We found that (a) working memory, motor activity, and language comprehension activated partially overlapping but mostly unique subregions of the cerebellum; (b) the linguistic portion of the cerebello-thalamo-cortical circuit was more extensive than the linguistic portion of the cortico-ponto-cerebellar tract; (c) there was a frontal-lobe bias in the connectivity from the cerebellum to the cerebrum; (d) there was some degree of specificity; and (e) for some cerebellar tracts, individual differences in picture identification ability covaried with fractional anisotropy metrics. These findings yield insights into the structural connectivity of the cerebellum as relates to the uniquely human process of language comprehension.</p>","PeriodicalId":34845,"journal":{"name":"Neurobiology of Language","volume":"5 3","pages":"652-675"},"PeriodicalIF":3.6000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11338303/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurobiology of Language","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1162/nol_a_00085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"LINGUISTICS","Score":null,"Total":0}
引用次数: 0

Abstract

Neurobiological models of receptive language have focused on the left-hemisphere perisylvian cortex with the assumption that the cerebellum supports peri-linguistic cognitive processes such as verbal working memory. The goal of this study was to identify language-sensitive regions of the cerebellum then map the structural connectivity profile of these regions. Functional imaging data and diffusion-weighted imaging data from the Human Connectome Project (HCP) were analyzed. We found that (a) working memory, motor activity, and language comprehension activated partially overlapping but mostly unique subregions of the cerebellum; (b) the linguistic portion of the cerebello-thalamo-cortical circuit was more extensive than the linguistic portion of the cortico-ponto-cerebellar tract; (c) there was a frontal-lobe bias in the connectivity from the cerebellum to the cerebrum; (d) there was some degree of specificity; and (e) for some cerebellar tracts, individual differences in picture identification ability covaried with fractional anisotropy metrics. These findings yield insights into the structural connectivity of the cerebellum as relates to the uniquely human process of language comprehension.

语言与小脑:与能说会道的大脑的结构连接。
接受性语言的神经生物学模型主要集中在左半球的小脑周围皮层,并假设小脑支持语言工作记忆等语言周围认知过程。本研究的目的是识别小脑的语言敏感区域,然后绘制这些区域的结构连接图谱。我们分析了来自人类连接组计划(HCP)的功能成像数据和扩散加权成像数据。我们发现:(a) 工作记忆、运动活动和语言理解激活了部分重叠但大部分独特的小脑亚区;(b) 大脑-小脑-皮层回路的语言部分比皮层-蓬托-小脑束的语言部分更广泛;(c) 从小脑到大脑的连接存在额叶偏倚;(d) 存在一定程度的特异性;(e) 对于某些小脑束,图像识别能力的个体差异与分数各向异性指标相关。这些发现有助于深入了解小脑结构连接与人类独特的语言理解过程之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Neurobiology of Language
Neurobiology of Language Social Sciences-Linguistics and Language
CiteScore
5.90
自引率
6.20%
发文量
32
审稿时长
17 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信