Contrast-free visualization of distal trigeminal nerve segments using MR neurography

IF 2.3 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Neuroimaging Pub Date : 2024-08-22 DOI:10.1111/jon.13230

Sulagna Sahu, Dane Hellwig, Zachary Morrison, Jeremy Hughes, Rosalind J. Sadleir

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引用次数: 0

Abstract

Background and Purpose

The 3-dimensional cranial nerve imaging (CRANI) sequence may assist visualization of anatomical details of extraforaminal cranial nerves and aid in clinical diagnosis and preoperative planning. In this study, we investigated the feasibility of using a combined CRANI and magnetization-prepared rapid-acquisition gradient-echo (MPRAGE) imaging protocol to comprehensively identify trigeminal nerve projections.

Method

We evaluated the detection of distal regions of three branches of the ophthalmic nerve (V1), three branches of the maxillary nerve (V2), and five branches of the mandibular nerve (V3) in seven healthy adult subjects, with and without contrast injection. Nerve branches were rated on a 5-point scale by three observers. Interobserver reliability was studied using weighted kappa statistics and percentage agreement.

Results

Among V1 and V2 branches, the frontal nerve and infraorbital nerve were most successfully identified (average rating of 3.9, agreement >80%) in precontrast MPRAGE images. In V3 branches, lingual and inferior alveolar nerves were most successfully identified (average rating of 3.9, agreement >80%) in precontrast CRANI images, with an excellent average rating. In all cases except one, interobserver reliability was rated good to excellent. The buccal nerve was the only branch with a low average interobserver rating. Gadolinium contrast did not improve nerve segment visualization in our study. This may relate to the specific anatomic regions assessed, gadolinium dose, postcontrast image timing, and lack of pathology.

Conclusion

A combined CRANI and MPRAGE protocol can be combined to visualize distal branches of V1, V2, and V3 and has potential for clinical use.

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利用磁共振神经成像技术无对比地观察三叉神经远端节段。

背景和目的：三维颅神经成像（CRANI）序列可帮助观察椎孔外颅神经的解剖细节，有助于临床诊断和术前计划。在这项研究中，我们探讨了使用 CRANI 和磁化预处理快速采集梯度回波（MPRAGE）联合成像方案全面识别三叉神经投射的可行性：我们评估了在注射和未注射造影剂的情况下，对七名健康成年受试者的三条眼神经分支（V1）、三条上颌神经分支（V2）和五条下颌神经分支（V3）远端区域的检测情况。神经分支由三名观察者以 5 分制评分。采用加权卡帕统计和百分比一致来研究观察者之间的可靠性：结果：在 V1 和 V2 神经分支中，额神经和眶下神经在对比前 MPRAGE 图像中的识别最为成功（平均评分为 3.9，一致性大于 80%）。在 V3 分支中，对比前 CRANI 图像中最成功识别的是舌神经和下牙槽神经（平均评分 3.9，一致度大于 80%），平均评分为优。除一个病例外，其他所有病例的观察者间可靠性均被评为良好至优秀。颊神经是唯一一个观察者间平均评分较低的分支。在我们的研究中，钆对比剂并没有改善神经节段的可视化。这可能与所评估的特定解剖区域、钆剂量、对比后成像时间以及缺乏病理学因素有关：结论：CRANI 和 MPRAGE 联合方案可用于观察 V1、V2 和 V3 的远端分支，具有临床应用潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuroimaging 医学-核医学

CiteScore

4.70

自引率

0.00%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Start reading the Journal of Neuroimaging to learn the latest neurological imaging techniques. The peer-reviewed research is written in a practical clinical context, giving you the information you need on: MRI CT Carotid Ultrasound and TCD SPECT PET Endovascular Surgical Neuroradiology Functional MRI Xenon CT and other new and upcoming neuroscientific modalities.The Journal of Neuroimaging addresses the full spectrum of human nervous system disease, including stroke, neoplasia, degenerating and demyelinating disease, epilepsy, tumors, lesions, infectious disease, cerebral vascular arterial diseases, toxic-metabolic disease, psychoses, dementias, heredo-familial disease, and trauma.Offering original research, review articles, case reports, neuroimaging CPCs, and evaluations of instruments and technology relevant to the nervous system, the Journal of Neuroimaging focuses on useful clinical developments and applications, tested techniques and interpretations, patient care, diagnostics, and therapeutics. Start reading today!