Effect of fractional picosecond laser therapy using a diffractive optical lens on histological tissue reaction.

IF 1.2 4区医学 Q3 DERMATOLOGY

Journal of Cosmetic and Laser Therapy Pub Date : 2024-01-01 Epub Date: 2024-08-22 DOI:10.1080/14764172.2024.2375384

Yun-Hee Rhee, Byung-Chul Park, Jee-Yeon Jung, Shin Hyuk Yoo, Ji-Hun Mo, Phil-Sang Chung

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引用次数: 0

Abstract

Background and objectives: Fractional ablative resurfacing techniques are preferred treatments for facial rejuvenation of aged skin. This study was performed to investigate the cutaneous effects of using a fractional picosecond laser at 1064 nm with a diffractive lens.

Methods: The penetration depth according to the location of the handpiece tip was evaluated using an acrylic panel. Laser induced optical breakdown (LIOB) and cutaneous damage were observed after hematoxylin and eosin staining in guinea pigs. Collagen formation was evaluated using Victoria staining, Masson's trichrome (MT) staining, and immunohistochemical staining for collagen type III.

Results: The penetration depth for LEVEL 1 was 499.98-935.23 μm (average: 668.75 ± 182.84 μm); the LIOB cavity area was 1664.17 ± 650.52 μm². The penetration depth of LEVEL 2 was 257.12-287.38 μm (average: 269.77 ± 14.55 μm) with an LIOB cavity area of 1335.85 ± 214.41 μm². At LEVEL 3, that was 36.17-53.69 μm (average: 52.15 ± 20.81 μm) and the LIOB cavity area was 1312.67 ± 1069.12 μm². No epidermal tissue damage was observed and collagen formation was observed from day 14 under all conditions.

Conclusion: Diffractive optical element (DOE) lens arranged laser treatment system controlled the position of LIOB occurrence and an irradiating area.

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使用衍射光学透镜的点阵皮秒激光疗法对组织反应的影响。

背景和目的：点阵消融换肤技术是面部老化皮肤年轻化的首选治疗方法。本研究旨在调查使用带有衍射透镜的 1064 纳米点阵皮秒激光的皮肤效果：方法：使用丙烯酸面板对手机尖端位置的穿透深度进行评估。在对豚鼠进行苏木精和伊红染色后，观察了激光诱导的光学击穿（LIOB）和皮肤损伤。使用维多利亚染色法、马森三色染色法（MT）和 III 型胶原蛋白免疫组化染色法评估胶原蛋白的形成：LEVEL 1 的穿透深度为 499.98-935.23 μm（平均：668.75 ± 182.84 μm）；LIOB 腔面积为 1664.17 ± 650.52 μm2。LEVEL 2 的穿透深度为 257.12-287.38 μm（平均：269.77 ± 14.55 μm），LIOB 腔面积为 1335.85 ± 214.41 μm2。在 LEVEL 3 中，表皮损伤为 36.17-53.69 μm（平均值：52.15 ± 20.81 μm），LIOB 腔面积为 1312.67 ± 1069.12 μm2。在所有条件下，均未观察到表皮组织损伤，从第 14 天起观察到胶原蛋白形成：结论：衍射光学元件（DOE）透镜排列的激光治疗系统控制了 LIOB 的发生位置和照射区域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cosmetic and Laser Therapy DERMATOLOGY-SURGERY

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues