Artificial Intelligence-Based Classification of CT Images Using a Hybrid SpinalZFNet.

IF 3.9 2区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Faiqa Maqsood, Wang Zhenfei, Muhammad Mumtaz Ali, Baozhi Qiu, Naveed Ur Rehman, Fahad Sabah, Tahir Mahmood, Irfanud Din, Raheem Sarwar
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Abstract

The kidney is an abdominal organ in the human body that supports filtering excess water and waste from the blood. Kidney diseases generally occur due to changes in certain supplements, medical conditions, obesity, and diet, which causes kidney function and ultimately leads to complications such as chronic kidney disease, kidney failure, and other renal disorders. Combining patient metadata with computed tomography (CT) images is essential to accurately and timely diagnosing such complications. Deep Neural Networks (DNNs) have transformed medical fields by providing high accuracy in complex tasks. However, the high computational cost of these models is a significant challenge, particularly in real-time applications. This paper proposed SpinalZFNet, a hybrid deep learning approach that integrates the architectural strengths of Spinal Network (SpinalNet) with the feature extraction capabilities of Zeiler and Fergus Network (ZFNet) to classify kidney disease accurately using CT images. This unique combination enhanced feature analysis, significantly improving classification accuracy while reducing the computational overhead. At first, the acquired CT images are pre-processed using a median filter, and the pre-processed image is segmented using Efficient Neural Network (ENet). Later, the images are augmented, and different features are extracted from the augmented CT images. The extracted features finally classify the kidney disease into normal, tumor, cyst, and stone using the proposed SpinalZFNet model. The SpinalZFNet outperformed other models, with 99.9% sensitivity, 99.5% specificity, precision 99.6%, 99.8% accuracy, and 99.7% F1-Score in classifying kidney disease.

Abstract Image

使用混合 SpinalZFNet 对 CT 图像进行基于人工智能的分类。
肾脏是人体的腹腔器官,负责过滤血液中多余的水分和废物。肾脏疾病的发生一般是由于某些补品、医疗条件、肥胖和饮食的变化,从而引起肾功能的变化,最终导致慢性肾病、肾衰竭和其他肾脏疾病等并发症。将患者元数据与计算机断层扫描(CT)图像相结合,对于准确及时地诊断此类并发症至关重要。深度神经网络(DNN)通过在复杂任务中提供高精确度,改变了医疗领域。然而,这些模型的高计算成本是一个重大挑战,尤其是在实时应用中。本文提出的 SpinalZFNet 是一种混合深度学习方法,它整合了脊柱网络(SpinalNet)的架构优势和 Zeiler 与 Fergus 网络(ZFNet)的特征提取能力,可利用 CT 图像对肾病进行准确分类。这种独特的组合增强了特征分析,显著提高了分类准确性,同时降低了计算开销。首先,使用中值滤波器对获取的 CT 图像进行预处理,然后使用高效神经网络(ENet)对预处理后的图像进行分割。之后,对图像进行增强,并从增强后的 CT 图像中提取不同的特征。提取的特征最终通过所提出的 SpinalZFNet 模型将肾病分为正常、肿瘤、囊肿和结石。在肾病分类方面,SpinalZFNet 的灵敏度为 99.9%,特异度为 99.5%,精确度为 99.6%,准确度为 99.8%,F1-Score 为 99.7%,均优于其他模型。
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来源期刊
Interdisciplinary Sciences: Computational Life Sciences
Interdisciplinary Sciences: Computational Life Sciences MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
8.60
自引率
4.20%
发文量
55
期刊介绍: Interdisciplinary Sciences--Computational Life Sciences aims to cover the most recent and outstanding developments in interdisciplinary areas of sciences, especially focusing on computational life sciences, an area that is enjoying rapid development at the forefront of scientific research and technology. The journal publishes original papers of significant general interest covering recent research and developments. Articles will be published rapidly by taking full advantage of internet technology for online submission and peer-reviewing of manuscripts, and then by publishing OnlineFirstTM through SpringerLink even before the issue is built or sent to the printer. The editorial board consists of many leading scientists with international reputation, among others, Luc Montagnier (UNESCO, France), Dennis Salahub (University of Calgary, Canada), Weitao Yang (Duke University, USA). Prof. Dongqing Wei at the Shanghai Jiatong University is appointed as the editor-in-chief; he made important contributions in bioinformatics and computational physics and is best known for his ground-breaking works on the theory of ferroelectric liquids. With the help from a team of associate editors and the editorial board, an international journal with sound reputation shall be created.
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