Essential oil composition and anti-inflammatory activity in wild citrus from northeast India

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-08-20 DOI:10.1016/j.bse.2024.104878

Aakash Maurya , Bhavya Priyadarshini Mishra , Ram Mohan , Vivek Kumar Sharma , Narayanan K. Nair , Alok Lehri , Tikam S. Rana

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Abstract

Citrus peel essential oil (PEO) is utilized in the food and juice processing, pharmaceuticals, and aroma industries due to various nutritional, pharmaceutical and cosmaceutical properties. In this study, the PEO of five wild Citrus species (Citrus medica, C. indica, C. latipes, C. hystrix, and C. cavaleriei) from northeast India, has been extracted using the hydro-distillation method. The oil yield varied from 0.02% to 0.32% (w/w). Gas Chromatography-Mass Spectrometry (GC-MS) analysis of citrus PEO showed the presence of 36 compounds in the range of 84.63–95.9%. Limonene was the major compound in the PEO, with the highest percentage in C. cavaleriei (80.86%), followed by C. hystrix (75.7%), medica (66.9%), C. indica (63.03%), and C. latipes (23.95%). Other compounds present in a considerable percentage were γ-terpinene (C. latipes, 16.86%; C. indica, 14.72%; C. medica, 6.73%), myrcene (C. indica, 5.34%), β-pinene (C. latipes, 9.49%), 3-carene (C. medica, 6.38%), (E)- β-caryophyllene (C. latipes, 6.07%), and neryl acetate (C. latipes, 6.10%). Anti-inflammatory assay of PEO in the five Citrus species revealed the highest anti-inflammatory activity in C. indica. The study suggests that wild citrus fruits can be an important source of limonene and other bioactive compounds with potential pharmaceutical and industrial applications.

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印度东北部野生柑橘的精油成分和抗炎活性

柑橘果皮精油（PEO）具有多种营养、药用和美容特性，可用于食品和果汁加工、制药和芳香产业。本研究采用水蒸馏法提取了印度东北部五种野生柑橘（Citrus medica、C. indica、C. latipes、C. hystrix 和 C. cavaleriei）的果皮精油。出油率从 0.02% 到 0.32%（重量比）不等。柑橘类 PEO 的气相色谱-质谱（GC-MS）分析表明，其中含有 36 种化合物，含量在 84.63-95.9% 之间。柠檬烯是 PEO 中的主要化合物，在 C. cavaleriei 中的比例最高（80.86%），其次是 C. hystrix（75.7%）、medica（66.9%）、C. indica（63.03%）和 C. latipes（23.95%）。占相当比例的其他化合物有γ-萜品烯（C. latipes，16.86%；C. indica，14.72%；C. medica，6.73%）、月桂烯（C. indica，5.34%）、β-蒎烯（C. latipes，9.49%）、3-蒈烯（C. medica，6.38%）、(E)-β-石竹烯（C. latipes，6.07%）和乙酸橙花酯（C. latipes，6.10%）。五种柑橘中 PEO 的抗炎测定显示，籼柑的抗炎活性最高。该研究表明，野生柑橘类水果是柠檬烯和其他生物活性化合物的重要来源，具有潜在的医药和工业应用价值。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.