Designing Patient-Reported Measures of Fertility: Cognitive Interview Findings from Adolescents and Young Adults with Cancer.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Mollie Rose Canzona, David E Victorson, Karly M Murphy, Marla L Clayman, Bryce B Reeve, Bonnie Patel, Ashley E Strahley, Thomas W McLean, Onengiya Harry, Michael E Roth, Regina V Smith, John M Salsman
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引用次数: 0

Abstract

Purpose: Fertility concerns (FC) are central to the well-being of many adolescent and young adult (AYA) cancer survivors. Clinical conversations about FC and fertility preservation are suboptimal, increasing patient distress. The goal of this project was to establish content validity and comprehensibility of self-report questions on FCs for AYAs with cancer. Methods: Following best practices, we conducted: (1) item identification, refinement, and generation; (2) translatability and reading level review; and (3) cognitive interviews. Items were reviewed by five AYAs in each round of cognitive interviews. Results: A systematic search yielded 63 measures and 873 items. Fifty items were subsequently modified to enhance clarity and relevance, representing subdomains of psychological and social/relational FC. Flesch-Kincaid analysis found 31 items written above the 6th grade level, which were subsequently revised. Translatability review resulted in the modification of 3 items. During cognitive interviews, 76% of AYAs found items easy to answer with 52% describing them as "very easy" and 24% as "somewhat easy." Sixty percent of participants indicated the items captured their experiences. The majority of those who reported items only somewhat reflected or did not reflect their experiences suggested items were simply not applicable for their particular case. Conclusion: This study is a critical step toward the foundation for an FC measurement system that is reliable, flexible, developmentally appropriate, comprehensible, translatable, and interpretable. Subsequent steps include psychometric testing to examine the construct validity and reliability of the FC items and calibration to enable the application of computer-adaptive testing and short form development. The evaluation will include potential item response bias by age range, gender identity, and race/ethnicity.

设计患者报告的生育力衡量标准:青少年和年轻成人癌症患者的认知访谈结果》(Cognitive Interview Findings from Adolescents and Young Adults with Cancer)。
目的:生育问题(FC)是许多青少年癌症幸存者的核心问题。有关生育问题和生育能力保护的临床对话并不理想,从而增加了患者的痛苦。本项目的目标是确定青少年和青年癌症患者有关生育问题的自我报告问题的内容有效性和可理解性。方法:按照最佳实践,我们进行了:(1)项目识别、完善和生成;(2)可翻译性和阅读水平审查;以及(3)认知访谈。在每一轮认知访谈中,由五名亚裔美国人对项目进行审查。结果:通过系统性搜索,得出了 63 个测量指标和 873 个项目。随后对 50 个项目进行了修改,以提高清晰度和相关性,这些项目代表了心理和社会/关系功能障碍的子域。弗莱什-金凯德分析发现,有 31 个项目的写作水平高于六年级水平,随后对其进行了修改。可译性审查导致修改了 3 个项目。在认知访谈中,76% 的青少年认为项目容易回答,52% 的人认为 "非常容易",24% 的人认为 "比较容易"。60% 的参与者表示这些项目反映了他们的经历。大多数人认为这些项目只在一定程度上反映或没有反映他们的经历,他们认为这些项目根本不适用于他们的具体情况。结论这项研究是为建立一个可靠、灵活、适合发展、可理解、可翻译和可解释的家庭功能测量系统而迈出的关键一步。随后的步骤包括心理测量测试,以检验功能分类项目的建构效度和信度,并进行校准,以便应用计算机自适应测试和开发简表。评估将包括不同年龄段、性别认同和种族/民族的潜在项目反应偏差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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