Protective effects of Allium jesdianum essential oil on rainbow trout (Oncorhynchus mykiss) exposed to sub-lethal toxicity of cypermethrin

IF 4.1 2区环境科学与生态学 Q1 MARINE & FRESHWATER BIOLOGY

Aquatic Toxicology Pub Date : 2024-08-13 DOI:10.1016/j.aquatox.2024.107051

Saeid Shahbazi Naserabad , Sarallah Zarei , Jamal Rahimi , Zaniar Ghafouri , Atta Mouludi-Saleh , Mahdi Banaee

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引用次数: 0

Abstract

This study aimed to investigate the protective effects of Allium jesdianum essential oil (AJEO) in decreasing cypermethrin toxicity for rainbow trout. First, the safety of the 0%, 0.5%, 1%, and 1.5% AJEO supplements was assayed after 60 days. Then, the protective effects of AJEO were studied on fish exposed to 12.5% 96h LC50 cypermethrin after 14 days. Results showed that 1 and 1.5% AJEO administration enhanced protease and lipase activities in the intestine and improved growth performance. Moreover, feeding fish with 1 and 1.5% AJEO increased catalase (CAT) and superoxide dismutase activities (SOD) and decreased malondialdehyde (MDA). Also, AJEO increased glutathione peroxidase (GPx) activity in serum. However, exposure to cypermethrin significantly decreased these enzyme activities and increased MDA. The oxidative biomarkers remained normal in fish fed with AJEO after exposure to cypermethrin. The administration of 1 and 1.5% AJEO significantly decreased cortisol and glucose levels, alkaline phosphatase (ALP), lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase activities. Although exposure to cypermethrin significantly increased these biochemical biomarkers, AJEO could adjust them. A significant effect of 1% AJEO on total protein and globulin was observed before and after exposure to cypermethrin. Exposure to cypermethrin decreased all immunological parameters in the serum and mucus. However, administration of 1% AJEO increased protease, lysozyme (LYS) activities, total immunoglobulin (Ig), complement C3 and C4, and nitroblue tetrazolium (NBT) in the serum and ALP, LYS, protease activities and Ig in mucus. In conclusion, results showed that AJEO could potentially decrease the toxicity effects of cypermethrin in fish.

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薤白精油对暴露于氯氰菊酯亚致死毒性的虹鳟鱼（Oncorhynchus mykiss）的保护作用

本研究旨在探讨精油（AJEO）在降低氯氰菊酯对虹鳟鱼毒性方面的保护作用。首先，在 60 天后检测了 0%、0.5%、1% 和 1.5% AJEO 补充剂的安全性。然后，研究了 AJEO 对接触 12.5% 氯氰菊酯（96 小时半数致死浓度）14 天的鱼类的保护作用。结果表明，添加 1% 和 1.5% 的 AJEO 可提高肠道中蛋白酶和脂肪酶的活性，改善生长性能。此外，投喂1%和1.5%的AJEO可提高过氧化氢酶（CAT）和超氧化物歧化酶（SOD）的活性，降低丙二醛（MDA）。此外，AJEO 还能提高血清中谷胱甘肽过氧化物酶（GPx）的活性。然而，接触氯氰菊酯会显著降低这些酶的活性并增加 MDA。暴露于氯氰菊酯后，用 AJEO 喂养的鱼的氧化生物标志物仍保持正常。投喂 1% 和 1.5% 的 AJEO 能明显降低皮质醇和葡萄糖水平、碱性磷酸酶 (ALP)、乳酸脱氢酶、天冬氨酸氨基转移酶和丙氨酸氨基转移酶活性。虽然接触氯氰菊酯会显著增加这些生化生物标志物，但 AJEO 可以调节它们。在接触氯氰菊酯前后，1%的AJEO对总蛋白和球蛋白有明显影响。接触氯氰菊酯会降低血清和粘液中的所有免疫参数。然而，施用 1%的 AJEO 会增加血清中的蛋白酶、溶菌酶（LYS）活性、总免疫球蛋白（Ig）、补体 C3 和 C4 以及硝基蓝四氮唑（NBT），并增加粘液中的 ALP、LYS、蛋白酶活性和 Ig。总之，研究结果表明，AJEO 有可能降低氯氰菊酯对鱼类的毒性作用。

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来源期刊

Aquatic Toxicology 环境科学-毒理学

CiteScore

7.10

自引率

4.40%

发文量

250

审稿时长

56 days

期刊介绍： Aquatic Toxicology publishes significant contributions that increase the understanding of the impact of harmful substances (including natural and synthetic chemicals) on aquatic organisms and ecosystems. Aquatic Toxicology considers both laboratory and field studies with a focus on marine/ freshwater environments. We strive to attract high quality original scientific papers, critical reviews and expert opinion papers in the following areas: Effects of harmful substances on molecular, cellular, sub-organismal, organismal, population, community, and ecosystem level; Toxic Mechanisms; Genetic disturbances, transgenerational effects, behavioral and adaptive responses; Impacts of harmful substances on structure, function of and services provided by aquatic ecosystems; Mixture toxicity assessment; Statistical approaches to predict exposure to and hazards of contaminants The journal also considers manuscripts in other areas, such as the development of innovative concepts, approaches, and methodologies, which promote the wider application of toxicological datasets to the protection of aquatic environments and inform ecological risk assessments and decision making by relevant authorities.