Oral Supplements and Dermatology: A Review

Abstract

Introduction

There is growing interest in the utility of oral supplements for improving overall health and wellness. Dietary supplements and nutraceuticals with antioxidant and anti-inflammatory properties have gained particular attention for their potential to optimize skin health. This review summarizes evidence for the following vitamins, minerals, and natural compounds in the realm of dermatology: niacinamide, vitamin D, vitamin C, vitamin E, zinc, omega-3 fatty acids, probiotics, polyphenols, Polypodium leucotomos, coenzyme Q10, and astaxanthin.

Results

Niacinamide and vitamins C, D, and E may all protect against UV damage. Zinc and omega-3 fatty acids may be useful for the treatment of acne and for minimizing side effects from isotretinoin. There is convincing evidence for the utility of probiotics in complementing standard treatments for acne, psoriasis, and atopic dermatitis. Collagen supplements have demonstrated anti-aging effects but should not be routinely recommended due to their unreliable quality. Antioxidants such as P. leucotomos, coenzyme Q10, astaxanthin, and polyphenols may play a role in anti-aging and photoprotection.

Conclusion

Oral supplements may play a beneficial role in skin health, namely in terms of photoprotection, anti-aging, and inflammatory conditions such as atopic dermatitis, acne, and psoriasis. However, further high-quality studies are needed.