Newborn congenital cytomegalovirus screening and hearing outcomes: a systematic review of current literature.

IF 1.9 4区医学 Q2 OTORHINOLARYNGOLOGY

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2024-10-01 Epub Date: 2024-07-26 DOI:10.1097/MOO.0000000000000996

Sarah A Pollick, Yusra Mansour, Megan H Pesch

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引用次数: 0

Abstract

Purpose of review: The purpose of this review is to summarize the very recent literature surrounding hearing outcomes of children with congenital cytomegalovirus (cCMV) detected through systematic screening programs.

Recent findings: There are several different approaches to cCMV screening including forms of targeted vs. universal screening of newborns as well as maternally-derived prenatal testing. However, many studies fail to document hearing-related outcomes both in the newborn period and further into childhood when late-onset sensorineural hearing loss (SNHL) can occur. This systematic review included studies of neonates screened for cCMV reporting hearing outcomes for at least one point in time. Hearing targeted screening appeared the most widely reported for detection of unilateral and bilateral SNHL in those with cCMV. A few studies examined these clinical findings in relation to antiviral treatment.

Summary: Congenital CMV is an important and common cause of childhood hearing loss. Newborn screening programs may expand opportunities for early diagnosis and treatment of the infection and its sequelae.

查看原文本刊更多论文

新生儿先天性巨细胞病毒筛查与听力结果：当前文献的系统性回顾。

综述目的：本综述旨在总结通过系统筛查计划发现患有先天性巨细胞病毒（cCMV）的儿童听力结果的最新文献：cCMV 筛查有几种不同的方法，包括对新生儿进行有针对性的筛查和普遍筛查，以及产前母体检测。然而，许多研究都没有记录新生儿期和儿童期的听力相关结果，因为儿童期可能会出现迟发性感音神经性听力损失 (SNHL)。本系统性综述纳入了对新生儿进行 cCMV 筛查的研究，这些研究报告了至少一个时间点的听力结果。有针对性的听力筛查似乎是用于检测 cCMV 患儿单侧和双侧 SNHL 的最广泛报道。小结：先天性巨细胞病毒是导致儿童听力损失的一个重要且常见的原因。新生儿筛查计划可为感染及其后遗症的早期诊断和治疗提供更多机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Otolaryngology & Head and Neck Surgery OTORHINOLARYNGOLOGY-

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Otolaryngology & Head and Neck Surgery is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With eleven disciplines published across the year – including maxillofacial surgery, head and neck oncology and speech therapy and rehabilitation – every issue also contains annotated references detailing the merits of the most important papers.