Revolutionizing deceased donor transplantation: How new approaches to machine perfusion broadens the horizon for organ donation

Q4 Medicine
Stephanie Almeida , William Snyder , Mita Shah , Jonathan Fisher , Christopher Marsh , Alana Hawkes , Diana Gorial , Sean DeWolf , Dianne B. McKay
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引用次数: 0

Abstract

Solid organ transplantation is lifesaving for persons with end-stage organ disease. Thanks to advancements in organ preservation, surgeons are now able to successfully transplant organs that were previously considered high risk for poor graft function. Innovations in perfusion machine types, preservation solutions and additives to preservation solutions have significantly improved the ability to utilize organs previously thought unusable.

Newer organ preservation techniques are offering a promising outlook for extending graft longevity and improving transplant outcomes. This review explores the impact of deceased donor type on graft quality and highlights emerging strategies designed to improve the function and viability of deceased donor organs.

已故捐献者移植的革命:机器灌注新方法如何拓宽器官捐献的视野
对于患有终末期器官疾病的人来说,实体器官移植是救命稻草。由于器官保存技术的进步,外科医生现在能够成功移植以前被认为移植功能差的高风险器官。灌注机类型、保存方案和保存方案添加剂方面的创新大大提高了利用以前被认为无法使用的器官的能力。本综述探讨了已故捐献者类型对移植物质量的影响,并重点介绍了旨在改善已故捐献者器官功能和存活率的新兴策略。
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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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