Nephroblastoma in Older Adult: Case Report and Review of Literature.

IF 0.7 Q4 ONCOLOGY

Case Reports in Oncology Pub Date : 2024-07-30 eCollection Date: 2024-01-01 DOI:10.1159/000540279

Ricardo Fernández-Ferreira, Jose Manuel Torres-Zazueta, César Martínez-Medrano, Adrián Meléndez-Mendoza, Sonia Tavares-García, María Alejandra Muñoz Rubiano, Gredel Portela-Rubio, Julieta Robles-Castro, Jorge Alberto Robles-Aviña, Jose Manuel Ruiz Morales

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引用次数: 0

Abstract

Introduction: Nephroblastoma, or Wilms' tumor, is a malignant renal neoplasm commonly found in children, is extremely rare in adults representing only 0.5% of all renal neoplasms. Adult Wilms tumor is rare, to our knowledge fewer than 300 cases have been reported in the English literature to date. However, in older adults after 60 years of age, only less than 45 cases have been reported. For this reason, treatment guidelines in adults still are lacking. Prognosis in nephroblastoma for adult patients is found to be worse than in children.

Case presentation: We report the case of a 65-year-old female with lumbar fossa mass, flank pain and hematuria, and pathologic diagnosis of Wilms tumor. We performed nephrectomy. No adjuvant treatment was given. Our patient remains asymptomatic and without evidence of recurrence 12 months after the surgery.

Conclusion: Nephroblastoma in the elderly presents different clinical behavior and prognosis compared to nephroblastoma in children.

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老年人肾母细胞瘤：病例报告和文献综述。

导言：肾母细胞瘤或 Wilms 瘤是一种常见于儿童的恶性肾肿瘤，在成人中极为罕见，仅占所有肾肿瘤的 0.5%。成人 Wilms 瘤非常罕见，据我们所知，迄今为止英文文献中报道的病例不到 300 例。然而，在 60 岁以后的老年人中，仅有不到 45 例的报道。因此，目前仍缺乏成人治疗指南。成年肾母细胞瘤患者的预后比儿童患者差：我们报告了一例 65 岁女性的病例，患者腰窝肿块、侧腹疼痛和血尿，病理诊断为 Wilms 肿瘤。我们为患者实施了肾切除术。没有进行辅助治疗。手术 12 个月后，患者仍无症状，也无复发迹象：结论：老年肾母细胞瘤的临床表现和预后与儿童肾母细胞瘤不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Oncology ONCOLOGY-

CiteScore

1.40

自引率

12.50%

发文量

151

审稿时长

7 weeks