Oscillatory potential findings in patients with acute ischaemic central retinal vein occlusion.

IF 2 Q2 OPHTHALMOLOGY
Ya Qu, Li Ran, Gang Wang, Min Wang, Shiying Li
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Abstract

Aims: To explore the sensitive components of full-field electroretinography (ERG) as indicators of retina function at the onset of acute ischaemic central retinal vein occlusion (CRVO).

Methods: 11 patients (11 eyes) with ischaemic CRVO and 32 patients (32 eyes) with non-ischaemic CRVO who presented with first-episode unilateral CRVO within 1 month of symptom onset and with no previous intervention were examined by the International Society for Clinical Electrophysiology of Vision standard ERG.

Results: A significant amplitude decline and peak time delay in light-adapted (LA) 3 ERG and LA 30 Hz flicker ERG (p<0.05 for all) was found in the ischaemic CRVO eyes, compared with the non-ischaemic CRVO eyes. The b/a amplitude ratio of dark-adapted (DA) 3 ERG, DA 10 ERG and LA 3 ERG was significantly different between the ischaemic and non-ischaemic groups (p<0.05 for all). Regarding oscillatory potentials (OPs), the amplitudes of OP1, OP2 and OP3 as well as the sum of DA 3 OP1-4 amplitudes (∑OPs) showed significant changes (p<0.01 for all) between two groups. No peak time delay of OPs was found between the ischaemic and non-ischaemic CRVO eyes.

Conclusion: The amplitude of DA 0.01 ERG, components of LA 3 ERG and LA 30 Hz flicker ERG, and the b/a amplitude ratio could be among the most sensitive indicators in patients with acute ischaemic CRVO. The amplitudes of OP1, OP2, OP3 and ∑OPs in the CRVO eyes were reduced to 40% of the control values, showing that this quantitative method is reliable for detecting ischaemic retinal diseases, even in early stage.

急性缺血性视网膜中央静脉闭塞患者的振荡电位发现。
目的:探讨在急性缺血性视网膜中央静脉闭塞(CRVO)发病时,全视场视网膜电图(ERG)的敏感成分作为视网膜功能的指标。方法:采用国际视力临床电生理学会标准ERG对11例缺血性CRVO患者(11眼)和32例非缺血性CRVO患者(32眼)进行检查,这些患者在症状出现后1个月内首次出现单侧CRVO,且之前未进行过干预:结果:光适应(LA)3 ERG和LA 30 Hz闪烁ERG的振幅明显下降,峰值时间明显延迟(p结论:DA 0.01 ERG 的振幅、LA 3 ERG 和 LA 30 Hz 闪烁 ERG 的成分以及 b/a 振幅比可能是急性缺血性 CRVO 患者最敏感的指标之一。CRVO眼的OP1、OP2、OP3和∑OP的振幅降低到对照值的40%,这表明这种定量方法即使在早期也能可靠地检测缺血性视网膜疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Open Ophthalmology
BMJ Open Ophthalmology OPHTHALMOLOGY-
CiteScore
3.40
自引率
4.20%
发文量
104
审稿时长
20 weeks
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