Epidemiology of respiratory infection pathogens using multiplex RT-qPCR in big earthquakes Area in Turkey (2023)

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Esin Dogantekin , Gönenç Caliskanturk , Selda Aslan , Akif Dogantekin
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引用次数: 0

Abstract

Introduction

The Kahramanmaraş earthquake, which has been classified as an earthquake with significant and destructive consequences on a global scale, has been referred to as "the disaster of the century.", occurred on February 6, 2023. A considerable number of structures were destroyed and a significant amount of damage was incurred in 11 provinces, including Kahramanmaraş. Respiratory tract infections are a serious public health problem seen in all age groups among earthquake victims living in tent and container cities.

Objective

The aim of the study was to determine the causative agents in respiratory tract samples taken for screening purposes from earthquake victims living in tent cities in the earthquake zone and to provide early diagnosis.

Method

Gaziantep Provincial Health Directorate Infectious Diseases Unit filiation teams collected nasopharyngeal swabs from earthquake victims living in tent cities around Gaziantep province between March 25 and March 30, 2023. The presence of 18 viruses and 6 bacteria that are causing respiratory tract infections were simultaneously detected by the Real-Time qPCR (RT-qPCR) technique.

Results

In the present study, respiratory pathogens were detected in 470 (56.62 %) of a total of 830 patients. The most frequently isolated agents were rhinovirus (20 %, 94/470), S. pneumoniae (12.87 %, 60/470), RSV A/B (12.12 %, 57/470), H. influenza type b (10. 85 %, 51/470) and others. Rhinovirus was the most frequently detected pathogen in the study. The coexistence of more than one pathogen was also detected. The most common association was found between HRV and S. pneumoniae (20.93 %, 9/43).

Conclusion

The results of the present study indicate that public health measures should be prioritized in natural disasters, and ıt demonstrates that infectious diseases became a significant problem in the time period after the earthquake. Early results can be obtained by screening viral and bacterial pathogen in respiratory tract samples with RT-qPCR, and an early diagnosis is ensured.

利用多重 RT-qPCR 在土耳其大地震灾区开展呼吸道感染病原体流行病学研究(2023 年)
导言 2023 年 2 月 6 日发生的卡赫拉曼马拉什地震被列为在全球范围内具有重大破坏性后果的地震,被称为 "世纪灾难"。包括卡赫拉曼马拉什在内的 11 个省的大量建筑被毁,损失惨重。在居住在帐篷城和集装箱城的地震灾民中,呼吸道感染是一个严重的公共卫生问题,可见于所有年龄段的人群。方法加济安泰普省卫生局传染病科亲子鉴定小组在 2023 年 3 月 25 日至 3 月 30 日期间收集了居住在加济安泰普省周边帐篷城的地震灾民的鼻咽拭子。采用实时 qPCR(RT-qPCR)技术同时检测了引起呼吸道感染的 18 种病毒和 6 种细菌。最常分离的病原体是鼻病毒(20%,94/470)、肺炎链球菌(12.87%,60/470)、RSV A/B(12.12%,57/470)、乙型流感嗜血杆菌(10.85%,51/470)和其他病原体。鼻病毒是研究中最常检测到的病原体。此外,还发现有一种以上的病原体同时存在。本研究结果表明,在自然灾害中应优先采取公共卫生措施。利用 RT-qPCR 筛查呼吸道样本中的病毒和细菌病原体可获得早期结果,确保早期诊断。
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来源期刊
Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.60
自引率
7.70%
发文量
218
审稿时长
66 days
期刊介绍: Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
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