Mohammad Daher, Oscar Covarrubias, Ryan Lopez, Peter Boufadel, Maria Catherine Rita Hachem, Ziad Zalaquett, Mohamad Y Fares, Joseph A Abboud
{"title":"The role of vitamin D in shoulder health: a comprehensive review of its impact on rotator cuff tears and surgical results.","authors":"Mohammad Daher, Oscar Covarrubias, Ryan Lopez, Peter Boufadel, Maria Catherine Rita Hachem, Ziad Zalaquett, Mohamad Y Fares, Joseph A Abboud","doi":"10.5397/cise.2024.00220","DOIUrl":null,"url":null,"abstract":"<p><p>Vitamin D deficiency is highly prevalent in the general population and is associated with various chronic health conditions. In addition to its role in bone mineralization, Vitamin D has various physiological effects that may impact the pathogenesis of shoulder pathologies. Vitamin D deficiency may also affect outcomes after shoulder surgeries, such as rotator cuff repair and total shoulder arthroplasty. Vitamin D plays a role in tissue healing, bone growth, and maintenance of homeostasis in skeletal muscle cells. Vitamin D also has anti-inflammatory effects that are important to rotator cuff health. Vitamin D deficiency is highly prevalent in patients with rotator cuff tears, suggesting its role as a potential risk factor. Vitamin D deficiency has been associated with decreased preoperative shoulder strength as well as increased re-tear rates, postoperative stiffness, and the need for revision surgery in patients who underwent rotator cuff repair. Studies have also demonstrated a potential association between vitamin D deficiency and increased risk of revision after total shoulder arthroplasty. Further research is necessary to elucidate the direct role of vitamin D in the pathogenesis of rotator cuff tears and its impact on clinical outcomes after rotator cuff surgery and total shoulder arthroplasty.</p>","PeriodicalId":33981,"journal":{"name":"Clinics in Shoulder and Elbow","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinics in Shoulder and Elbow","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5397/cise.2024.00220","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Vitamin D deficiency is highly prevalent in the general population and is associated with various chronic health conditions. In addition to its role in bone mineralization, Vitamin D has various physiological effects that may impact the pathogenesis of shoulder pathologies. Vitamin D deficiency may also affect outcomes after shoulder surgeries, such as rotator cuff repair and total shoulder arthroplasty. Vitamin D plays a role in tissue healing, bone growth, and maintenance of homeostasis in skeletal muscle cells. Vitamin D also has anti-inflammatory effects that are important to rotator cuff health. Vitamin D deficiency is highly prevalent in patients with rotator cuff tears, suggesting its role as a potential risk factor. Vitamin D deficiency has been associated with decreased preoperative shoulder strength as well as increased re-tear rates, postoperative stiffness, and the need for revision surgery in patients who underwent rotator cuff repair. Studies have also demonstrated a potential association between vitamin D deficiency and increased risk of revision after total shoulder arthroplasty. Further research is necessary to elucidate the direct role of vitamin D in the pathogenesis of rotator cuff tears and its impact on clinical outcomes after rotator cuff surgery and total shoulder arthroplasty.
维生素 D 缺乏症在普通人群中非常普遍,并与各种慢性疾病相关。除了在骨矿化中的作用外,维生素 D 还具有各种生理效应,可能会影响肩部病变的发病机制。缺乏维生素 D 还可能影响肩部手术(如肩袖修复术和全肩关节置换术)后的效果。维生素 D 在组织愈合、骨骼生长和维持骨骼肌细胞平衡方面发挥着作用。维生素 D 还具有抗炎作用,对肩袖健康非常重要。肩袖撕裂患者普遍缺乏维生素 D,这表明维生素 D 是一个潜在的风险因素。维生素 D 缺乏与肩袖修复患者术前肩部力量下降、再次撕裂率增加、术后僵硬以及需要进行翻修手术有关。研究还表明,维生素 D 缺乏与全肩关节置换术后翻修风险增加之间存在潜在联系。要阐明维生素 D 在肩袖撕裂发病机制中的直接作用及其对肩袖手术和全肩关节置换术后临床效果的影响,还需要进一步的研究。