Therapeutic efficacy of cold atmospheric plasma in four golden retrievers with acute otitis externa.

IF 1.9 3区 农林科学 Q3 DERMATOLOGY
Veterinary dermatology Pub Date : 2024-12-01 Epub Date: 2024-08-14 DOI:10.1111/vde.13287
Alanur Bakır, Claudia Susanne Nett-Mettler, Bulent Ulutas
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Abstract

Background: Cold atmospheric plasma (CAP) is a new therapeutic tool used to treat various skin diseases in humans and animals.

Objective: To evaluate the effect of CAP in the treatment of canine acute otitis externa (AOE).

Animals: Four client-owned golden retriever dogs with bilateral AOE.

Methods and materials: After cleaning with a commercial ear cleanser, right ears (STANDARD group) were treated with an antibiotic/antifungal/corticosteroid combination and left ears (CAP group) were treated with CAP every three days for a total of four treatments. Cytological score and otitis index score (OTIS)3 were recorded for each ear on Day (D)0, D10 and D15. At D10 and D15, owners and investigators recorded an overall assessment.

Results: In both groups, OTIS3 and cytological score decreased over the study period. The overall assessment scale ranged from moderate to excellent in both groups.

Conclusions and clinical relevance: Cold atmospheric plasma treatment showed equal therapeutic effect compared with a commercial topical anti-inflammatory and antimicrobial ear treatment.

冷大气等离子体对四只患有急性外耳道炎的金毛猎犬的治疗效果。
背景:冷大气等离子体(CAP)是一种新的治疗工具,可用于治疗人类和动物的各种皮肤病:评估 CAP 治疗犬急性外耳道炎 (AOE) 的效果:四只患有双侧急性外耳道炎的客户饲养的金毛猎犬:在使用商业洗耳液清洁耳朵后,右耳(标准组)接受抗生素/抗真菌/皮质类固醇联合治疗,左耳(CAP 组)接受 CAP 治疗,每三天一次,共治疗四次。在第 0 天、第 10 天和第 15 天记录每只耳朵的细胞学评分和耳炎指数评分 (OTIS)3。在第 10 天和第 15 天,饲养者和调查人员记录总体评估结果:在研究期间,两组的 OTIS3 和细胞学评分均有所下降。结论和临床意义:结论和临床意义:冷大气等离子体治疗与商用外用消炎药和抗菌药耳部治疗相比,具有相同的治疗效果。
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来源期刊
Veterinary dermatology
Veterinary dermatology 农林科学-兽医学
CiteScore
3.20
自引率
21.40%
发文量
92
审稿时长
12-24 weeks
期刊介绍: Veterinary Dermatology is a bi-monthly, peer-reviewed, international journal which publishes papers on all aspects of the skin of mammals, birds, reptiles, amphibians and fish. Scientific research papers, clinical case reports and reviews covering the following aspects of dermatology will be considered for publication: -Skin structure (anatomy, histology, ultrastructure) -Skin function (physiology, biochemistry, pharmacology, immunology, genetics) -Skin microbiology and parasitology -Dermatopathology -Pathogenesis, diagnosis and treatment of skin diseases -New disease entities
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