The Prevalence of Comorbidities Associated with Multiple Sclerosis in Saudi Arabia.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Annals of African Medicine Pub Date : 2024-10-01 Epub Date: 2024-08-13 DOI:10.4103/aam.aam_49_24
Hind Alnajashi, Abdullah Wali, Ali Aqeeli, Almothanna Magboul, Mohammed Alfulayt, Abdullah Baasher, Samer Alzahrani
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引用次数: 0

Abstract

Background: Multiple sclerosis (MS) is a chronic, immune mediated demyelinating illness of the central nervous system. This study looks at various comorbidities associated with MS, focusing on their impact on disease progression. Understanding comorbidities in MS is important as it can impact treatment selection and overall disease management and prognosis.

Aims and objectives: Our aim is to show the prevalence of comorbidities along with MS. This research focuses on the comorbidities associated with MS and their impact on disease progression in the Arab Gulf region, with a special emphasis on Jeddah, Saudi Arabia.

Material and methods: A retrospective record review was conducted from July 2022 to July 2023. The study included 286 patients, selected based on a definitive MS diagnosis in accordance with McDonald's 2017 criteria. Data collected included demographic information, MS type, duration of diagnosis, type of disease modifying therapy (DMT) used, Expanded Disability Status Scale (EDSS) score, and type of comorbidities.

Results: The majority of the patients were female (70%) with an average age of 36 years. Most patients had relapsing remitting MS, and the majority were on DMTs, with fingolimod being the most common. Nearly half of the patients had comorbidities, with mood disorders, diabetes mellitus (DM), migraine, and hypertension (HTN) being prevalent. A significant positive association was found between the EDSS scores and both DM and HTN, but there was no significant link with migraine.

Conclusion: The findings indicate that individuals with MS have an increased risk of developing comorbidities such as migraine, DM, and HTN. Emphasizing a healthy lifestyle could potentially reduce the incidence of DM and HTN and their related vascular complications. The research also notes the prevalence of mood disorders among the MS population, although it remains inconclusive whether these are separate comorbid conditions or inherent symptoms of MS.

沙特阿拉伯多发性硬化症相关并发症的患病率。
背景:多发性硬化症(MS)是一种免疫介导的慢性中枢神经系统脱髓鞘疾病。本研究探讨了与多发性硬化症相关的各种合并症,重点关注它们对疾病进展的影响。了解多发性硬化症的合并症非常重要,因为这可能会影响治疗选择、整体疾病管理和预后:我们的目的是显示多发性硬化症合并症的发病率。这项研究的重点是与多发性硬化症相关的合并症及其对阿拉伯海湾地区疾病进展的影响,尤其侧重于沙特阿拉伯的吉达:从 2022 年 7 月至 2023 年 7 月进行了一项回顾性记录审查。研究共纳入 286 名患者,这些患者是根据 2017 年麦克唐纳标准确诊的多发性硬化症患者筛选出来的。收集的数据包括人口统计学信息、多发性硬化症类型、诊断持续时间、使用的疾病调整疗法(DMT)类型、残疾状况扩展量表(EDSS)评分以及合并症类型:大多数患者为女性(70%),平均年龄为 36 岁。大多数患者患有复发缓解型多发性硬化症,大多数患者正在服用 DMTs,其中芬戈莫德最为常见。近一半的患者患有合并症,其中以情绪障碍、糖尿病(DM)、偏头痛和高血压(HTN)最为常见。研究发现,EDSS评分与糖尿病和高血压之间存在明显的正相关,但与偏头痛之间没有明显联系:研究结果表明,多发性硬化症患者罹患偏头痛、糖尿病和高血压等合并症的风险增加。强调健康的生活方式有可能降低糖尿病和高血压的发病率及其相关的血管并发症。研究还注意到情绪障碍在多发性硬化症患者中的普遍性,但这些是单独的合并症还是多发性硬化症的固有症状仍无定论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annals of African Medicine
Annals of African Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
31
期刊介绍: The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
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