Levels of IgG to Food Antigens in Practically Healthy People and with Metabolic Syndrome

IF 0.6 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
V. P. Patrakeeva, A. V. Samodova, V. A. Shtaborov, L. K. Dobrodeeva
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引用次数: 0

Abstract

The study compared the content of IgG specific to 90 food antigens in practically healthy people and in people with metabolic syndrome. It has been shown that IgG levels to food antigens are higher in metabolic syndrome, which may be due to an increase in the activity of paracellular transport of food antigens and disruption of the intestinal barrier function caused by the influence of proinflammatory cytokines and hyperglycemia. Gender characteristics of IgG content to food antigens were established, with a significant increase in them in women against the background of a higher level of markers of general inflammation both in the group of practically healthy people and in those with metabolic syndrome.

Abstract Image

Abstract Image

健康人和代谢综合征患者的食物抗原 IgG 水平
摘要 该研究比较了健康人和代谢综合征患者体内 90 种食物抗原特异性 IgG 的含量。研究表明,代谢综合征患者的食物抗原 IgG 含量较高,这可能是由于食物抗原的细胞旁转运活性增加,以及促炎细胞因子和高血糖的影响导致肠道屏障功能破坏。研究还确定了食物抗原 IgG 含量的性别特征,在一般炎症标志物水平较高的背景下,女性的食物抗原 IgG 含量显著增加,无论是在身体健康的人群中还是在患有代谢综合征的人群中都是如此。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
31
期刊介绍: Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry   covers all major aspects of biomedical chemistry and related areas, including proteomics and molecular biology of (patho)physiological processes, biochemistry, neurochemistry, immunochemistry and clinical chemistry, bioinformatics, gene therapy, drug design and delivery, biochemical pharmacology, introduction and advertisement of new (biochemical) methods into experimental and clinical medicine. The journal also publishes review articles. All issues of the journal usually contain solicited reviews.
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