{"title":"Upper bounds on overshoot in SIR models with nonlinear incidence","authors":"Maximilian M. Nguyen","doi":"10.1038/s44260-024-00010-2","DOIUrl":null,"url":null,"abstract":"We expand the calculation of the upper bound on epidemic overshoot in SIR models to account for nonlinear incidence. We lay out the general procedure and restrictions to perform the calculation analytically for nonlinear functions in the number of susceptibles. We demonstrate the procedure by working through several examples and also numerically study what happens to the upper bound on overshoot when nonlinear incidence manifests in the form of epidemic dynamics over a contact network. We find that both steeper incidence terms and larger contact heterogeneity can increase the range of communicable diseases at which the overshoot remains a relatively large public health hazard.","PeriodicalId":501707,"journal":{"name":"npj Complexity","volume":" ","pages":"1-7"},"PeriodicalIF":0.0000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s44260-024-00010-2.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"npj Complexity","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44260-024-00010-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We expand the calculation of the upper bound on epidemic overshoot in SIR models to account for nonlinear incidence. We lay out the general procedure and restrictions to perform the calculation analytically for nonlinear functions in the number of susceptibles. We demonstrate the procedure by working through several examples and also numerically study what happens to the upper bound on overshoot when nonlinear incidence manifests in the form of epidemic dynamics over a contact network. We find that both steeper incidence terms and larger contact heterogeneity can increase the range of communicable diseases at which the overshoot remains a relatively large public health hazard.
我们扩展了 SIR 模型中流行病超调上限的计算方法,以考虑非线性发生率。我们列出了针对易感者数量的非线性函数进行分析计算的一般程序和限制条件。我们通过几个例子演示了这一过程,并用数值方法研究了当非线性发生率以接触网络上流行动态的形式出现时,超调的上限会发生什么变化。我们发现,更陡峭的发病率项和更大的接触异质性都会扩大传染病的范围,在这种情况下,过冲仍会对公共健康造成相对较大的危害。