Two undescribed monoterpenoids from the fruit of Gardenia jasminoides Ellis

IF 1.3 4区生物学 Q4 CHEMISTRY, MEDICINAL

Phytochemistry Letters Pub Date : 2024-08-12 DOI:10.1016/j.phytol.2024.08.003

Di Lu , Yan-Gang Cao , Yan-Ling Liu , Xu Chen , Xiang-Da Li , Xin-Yi Ma , Ying Niu , Xiao-Ke Zheng , Wei-Sheng Feng

引用次数: 0

Abstract

Two uncharacterized monoterpenoids (1–2) and six known analogues (3–8) were isolated from the fruit of Gardenia jasminoides. Their structures were determined by comprehensive spectroscopic data analysis, and the absolute configuration of 2 was elucidated by comparing the calculated electronic circular dichroism (ECD) spectrum with experimental ECD spectrum. Additionally, the results of preliminary activity evaluation indicated that these compounds showed slightly α-glucosidase inhibitory activity.

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从栀子果实中提取的两种未曾描述过的单萜物质 Ellis

从栀子果实中分离出了两种未定性的单萜（1-2）和六种已知的类似物（3-8）。通过全面的光谱数据分析确定了它们的结构，并通过比较计算得出的电子圆二色性（ECD）光谱和实验得出的 ECD 光谱，阐明了 2 的绝对构型。此外，初步活性评价结果表明，这些化合物具有轻微的α-葡萄糖苷酶抑制活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Phytochemistry Letters 生物-生化与分子生物学

CiteScore

3.00

自引率

11.80%

发文量

190

审稿时长

34 days

期刊介绍： Phytochemistry Letters invites rapid communications on all aspects of natural product research including: • Structural elucidation of natural products • Analytical evaluation of herbal medicines • Clinical efficacy, safety and pharmacovigilance of herbal medicines • Natural product biosynthesis • Natural product synthesis and chemical modification • Natural product metabolism • Chemical ecology • Biotechnology • Bioassay-guided isolation • Pharmacognosy • Pharmacology of natural products • Metabolomics • Ethnobotany and traditional usage • Genetics of natural products Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.