Scalable synthesis of the L/N ring of maitotoxin

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2024-07-29 DOI:10.1016/j.tetlet.2024.155221

引用次数: 0

Abstract

A scalable method for synthesizing the L/N ring of maitotoxin corresponding to an unnatural l-glucose derivative was developed via the MacMillan method and C-glycosylation under flow conditions. The longest linear sequence from Z-2-buten-1,4-diol was 7 steps with 10 total steps.

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麦角毒素 L/N 环的规模化合成

通过 MacMillan 法和流动条件下的 C-糖基化，开发了一种可扩展的方法，用于合成与非天然 l-葡萄糖衍生物相对应的麦角毒素 L/N 环。从 Z-2-buten-1,4-diol 开始的最长线性序列为 7 步，共 10 步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.