The cost-effectiveness of a co-managed care model for elderly hip fracture patients in China: a modelling study

IF 7.6 1区 医学 Q1 HEALTH CARE SCIENCES & SERVICES
Lizheng Xu , Minghui Yang , Xinyi Zhang , Jing Zhang , Jiusheng He , Liangyuan Wen , Xianhai Wang , Zongxin Shi , Sanbao Hu , Fengpo Sun , Zishun Gong , Mingyao Sun , Ke Peng , Pengpeng Ye , Ruofei Ma , Xinbao Wu , Mingsheng Chen , Stephen Jan , Rebecca Ivers , Maoyi Tian , Lei Si
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引用次数: 0

Abstract

Background

The clinical effectiveness of multidisciplinary co-managed care for hip fracture patients in China has been demonstrated in a multicenter non-randomized controlled study. This study aims to estimate the cost-effectiveness of the co-managed care.

Methods

The study is based on a multicenter clinical trial (n = 2071) in China. We developed a state transition microsimulation model to estimate the cost-effectiveness of the co-managed care compared with usual care for hip fracture patients from healthcare system perspective. The costs incorporated into the model included hospitalization costs, post-discharge expenses, and secondary fracture therapy costs. Effectiveness was measured using quality-adjusted life years (QALYs). Costs and effects were discounted at 5% annually. A simulation cycle length of 1-year and a lifetime horizon were employed. The cost-effectiveness threshold was established at USD 37,118. To address uncertainties, one-way deterministic sensitivity analysis and probabilistic sensitivity analysis were conducted.

Findings

In the base case analysis, the co-managed care group had a lifetime cost of USD 31,571 and achieved an effectiveness of 3.22 QALYs, whereas the usual care group incurred a cost of USD 27,878 and gained 2.85 QALYs. The incremental cost-effectiveness ratio was USD 9981 per QALY gained; thus the co-managed care model was cost-effective. The cost-effectiveness was sensitive to the age of having hip fractures and hospitalization costs in the intervention group.

Interpretation

The co-managed care in hip fracture patients represents value for money, and should be scaled up and prioritized for funding in China.

Funding

The study is supported by Capital's Funds for Health Improvement and Research (2022-1-2071, 2018-1-2071).

中国老年髋部骨折患者共同管理护理模式的成本效益:一项模型研究
背景一项多中心非随机对照研究显示,在中国对髋部骨折患者进行多学科联合管理治疗具有临床疗效。本研究旨在估算联合管理护理的成本效益。方法本研究基于中国的一项多中心临床试验(n = 2071)。我们建立了一个状态转换微观模拟模型,从医疗系统的角度估算髋部骨折患者接受联合管理护理与常规护理的成本效益。模型中的成本包括住院费用、出院后费用和二次骨折治疗费用。疗效以质量调整生命年(QALYs)来衡量。成本和效果的贴现率为每年 5%。模拟周期长度为 1 年,时间跨度为终生。成本效益阈值定为 37,118 美元。在基础病例分析中,共同管理护理组的终生成本为 31,571 美元,获得了 3.22 QALYs 的疗效,而常规护理组的成本为 27,878 美元,获得了 2.85 QALYs 的疗效。每获得 1 QALY 的增量成本效益比为 9981 美元;因此,共同管理护理模式具有成本效益。干预组的成本效益对髋部骨折患者的年龄和住院费用敏感。释义髋部骨折患者的联合管理护理具有成本效益,应在中国推广并优先获得资助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
The Lancet Regional Health: Western Pacific
The Lancet Regional Health: Western Pacific Medicine-Pediatrics, Perinatology and Child Health
CiteScore
8.80
自引率
2.80%
发文量
305
审稿时长
11 weeks
期刊介绍: The Lancet Regional Health – Western Pacific, a gold open access journal, is an integral part of The Lancet's global initiative advocating for healthcare quality and access worldwide. It aims to advance clinical practice and health policy in the Western Pacific region, contributing to enhanced health outcomes. The journal publishes high-quality original research shedding light on clinical practice and health policy in the region. It also includes reviews, commentaries, and opinion pieces covering diverse regional health topics, such as infectious diseases, non-communicable diseases, child and adolescent health, maternal and reproductive health, aging health, mental health, the health workforce and systems, and health policy.
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