Tumor phyllodes maligno asociado a carcinoma ductal infiltrante de la mama, descripción de un caso tratado en nuestro centro

Abstract

The association of Phyllodes tumor with malignant epithelial neoplasms is very rare, which is why the presentation of a case recently treated in our unit is of interest. This article describes our experience in the diagnosis and treatment of a 72-year-old patient diagnosed with a Phyllodes tumor of the breast associated with a triple-negative infiltrating ductal carcinoma and aims to draw attention to this very rare association. The association of Phyllodes tumor and carcinoma occurs in only 1–2% of all phyllodes tumors. Types of carcinomas include carcinoma in situ, invasive forms ductal, lobular, tubular and squamous carcinoma, with the ductal phenotype being the most frequently related usually located inside or adjacent to the phyllodes tumor, since the carcinoma originates from the epithelial component of this tumor. Detecting the carcinomatous component prior to surgical intervention is very difficult, being diagnosed in most cases in the definitive pathological study. The main treatment is surgery with wide margins, sometimes combining SLNB, if it is associated with a carcinoma. A detailed analysis of tumor characteristics with reference to molecular subtype and pathological features should be performed to select the optimal treatment strategy for Phyllodes tumor-associated carcinoma.