Influence of the Morphological Characteristics and Filling of Polylactide Matrices on the Proliferation of HEK293T Cells

IF 0.8 Q3 Engineering

Nanotechnologies in Russia Pub Date : 2024-08-06 DOI:10.1134/S2635167624600421

A. M. Azieva, D. A. Kirillova, E. V. Yastremsky, R. V. Sharikov, N. A. Sharikova, K. G. Antipova, T. E. Grigoriev, A. L. Vasiliev

引用次数: 0

Abstract

The adhesion, proliferation, differentiation, and other types of interaction of a cell culture with synthetic biocompatible matrices completely depend on the type of cells, as well as on the structure, filling, and surface of the matrix itself. The results of studying the proliferation of HEK293T cells on polylactide matrices of various architectures are presented. An estimate of the rate of cell proliferation is obtained for oriented and nonoriented spongy and nonwoven fibrous matrices, as well as composite polylactide matrices with collagen and chitosan.

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聚乳酸基质的形态特征和填充物对 HEK293T 细胞增殖的影响

摘要细胞培养物与合成生物相容性基质的粘附、增殖、分化和其他类型的相互作用完全取决于细胞的类型以及基质本身的结构、填充物和表面。本文介绍了研究 HEK293T 细胞在不同结构的聚乳酸基质上增殖的结果。对定向和非定向海绵状纤维基质、无纺布纤维基质以及含有胶原蛋白和壳聚糖的复合聚乳酸基质的细胞增殖率进行了估算。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.